A Rule-Based method to model myocardial fiber orientation for simulating ventricular outflow tract arrhythmias

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• dc.contributor.author Doste Beltrán, Rubén
• dc.contributor.author Soto-Iglesias, David
• dc.contributor.author Bernardino Perez, Gabriel
• dc.contributor.author Sebastián Aguilar, Rafael, 1978-
• dc.contributor.author Giffard-Roisin, Sophie
• dc.contributor.author Cabrera-Lozoya, Rocío
• dc.contributor.author Sermesant, Maxime
• dc.contributor.author Berruezo Sánchez, Antonio
• dc.contributor.author Sánchez-Quintana, Damián
• dc.contributor.author Camara, Oscar
• dc.date.accessioned 2019-11-22T15:24:46Z
• dc.date.available 2019-11-22T15:24:46Z
• dc.date.issued 2017
• dc.description Comunicació presentada a: FIMH 2017 9th International Conference, celebrada a Toronto, Canadà, de l'11 al 13 de juny de 2017.ca
• dc.description.abstract Myocardial fiber orientation determines the propagation of electrical waves in the heart and the contraction of cardiac tissue. One common approach for assigning fiber orientation to cardiac anatomi- cal models are Rule-Based Methods (RBM). However, RBM have been developed to assimilate data mostly from the Left Ventricle. In conse- quence, fiber information from RBM does not match with histological data in other areas of the heart, having a negative impact in cardiac simulations beyond the LV. In this work, we present a RBM where fiber orientation is separately modeled in each ventricle following observations from histology. This allows to create detailed fiber orientation in specific regions such as the right ventricle endocardium, the interventricular sep- tum and the outow tracts. Electrophysiological simulations including these anatomical structures were then performed, with patient-specific data of outow tract ventricular arrhythmias (OTVA) cases. A compar- ison between the obtained simulations and electro-anatomical data of these patients confirm the potential for in silico identification of the site of origin in OTVAs before the intervention.
• dc.description.sponsorship This work was partially funded by the European Union under the Horizon 2020 Programme for Research, Innovation (grant agreement No. 642676 CardioFunX- ion)en
• dc.format.mimetype application/pdf
• dc.identifier.citation Doste R, Soto-Iglesias D, Bernardino G, Sebastian R, Giffard-Roisin S, Cabrera-Lozoya R, Sermesant M, Berruezo A, Sánchez-Quintana D, Camara O. A Rule-Based method to model myocardial fiber orientation for simulating ventricular outflow tract arrhythmias. In: Pop M, Wright GA, editors. Functional Imaging and Modelling of the Heart 9th International Conference, FIMH 2017 Proceedings; 2017 11-13 Jun; Toronto, Canada. Cham: Springer; 2017. p. 344-53. (LNCS; no. 10263). DOI: 10.1007/978-3-319-59448-4_33
• dc.identifier.doi http://dx.doi.org/10.1007/978-3-319-59448-4_33
• dc.identifier.isbn 978-3-319-59447-7
• dc.identifier.issn 0302-9743
• dc.identifier.uri http://hdl.handle.net/10230/42942
• dc.language.iso eng
• dc.publisher Springer
• dc.relation.ispartof Pop M, Wright GA, editors. Functional Imaging and Modelling of the Heart 9th International Conference, FIMH 2017 Proceedings; 2017 11-13 Jun; Toronto, Canada. Cham: Springer; 2017. p. 344-53. (LNCS; no. 10263).
• dc.relation.projectID info:eu-repo/grantAgreement/EC/H2020/642676
• dc.rights © Springer The final publication is available at Springer via http://dx.doi.org/10.1007/978-3-319-59448-4_33
• dc.rights.accessRights info:eu-repo/semantics/openAccess
• dc.subject.keyword Fiber orientationen
• dc.subject.keyword Rule-based methoden
• dc.subject.keyword Electrophysiological simulationsen
• dc.subject.keyword Arrhythmiasen
• dc.subject.keyword Outflow tractsen
• dc.title A Rule-Based method to model myocardial fiber orientation for simulating ventricular outflow tract arrhythmias
• dc.type info:eu-repo/semantics/conferenceObject
• dc.type.version info:eu-repo/semantics/acceptedVersion