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Welcome to the UPF Digital Repository

The institutional repository collects, disseminates and preserves, in digital form, the intellectual output that results from the academic and research activity of the UPF and also the scientific magazines and the institutional publications. Its purpose is to increase the impact of research done at the UPF and its intellectual memory.

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Recently Added

Integrated analysis of germline and tumor DNA identifies new candidate genes involved in familial colorectal cancer

Usuari de càrrega (MDPI, 2019)
Systems genetics of hepatic metabolome reveals octopamine as a target for non-alcoholic fatty liver disease treatment

Gut, Ivo Glynne (Nature Research, 2019)
The cochaperone CHIP marks Hsp70- and Hsp90-bound substrates for degradation through a very flexible mechanism

Sabidó Aguadé, Eduard, 1981- (Nature Research, 2019)
Tuberculosis exacerbates HIV-1 infection through IL-10/STAT3-dependent tunneling nanotube formation in macrophages

Souriant, Shanti; Lastrucci, Claire; Vérollet, Christel (Elsevier, 2019)

The tuberculosis (TB) bacillus, Mycobacterium tuberculosis (Mtb), and HIV-1 act synergistically; however, the mechanisms by which Mtb exacerbates HIV-1 pathogenesis are not well known. Using in vitro and ex vivo cell culture ...
Single cell RNA-seq identifies the origins of heterogeneity in efficient cell transdifferentiation and reprogramming

Francesconi, Mirko; Di Stefano, Bruno, 1984-; Berenguer, Clara; de Andrés-Aguayo, Luisa; Plana-Carmona, Marcos; Mendez-Lago, Maria; Guillaumet-Adkins, Amy; Rodríguez Esteban, Gustavo; Gut, Marta; Gut, Ivo Glynne; Heyn, Holger; Lehner, Ben, 1978-; Graf, T. (Thomas) (eLife, 2019)

Forced transcription factor expression can transdifferentiate somatic cells into other specialised cell types or reprogram them into induced pluripotent stem cells (iPSCs) with variable efficiency. To better understand the ...