Human iPSC-Chimera xenotransplantation and the non-identity problem

Mostra el registre complet Registre parcial de l'ítem

• dc.contributor.author Casal, Paula
• dc.contributor.author Williams, Andrew
• dc.date.accessioned 2023-01-24T07:13:55Z
• dc.date.available 2023-01-24T07:13:55Z
• dc.date.issued 2019
• dc.description.abstract Xenotransplantation is often deemed morally objectionable because of the costs it imposes on the organ donor and the risks it imposes on the recipient. For some, involving human–pig chimeras as donors makes the practice more objectionable or even abhorrent from the start. For others, by contrast, using such chimeras weakens recipient-based objections because it reduces the risk of organ rejection and malfunctioning, and cancels donor-based objections because the practice does not harm chimeras but instead gives them valuable lives they would not otherwise have. The paper examines and eventually rejects the latter defense. It also discusses the additional risks of chimeric xenotourism in countries with less demanding procedural guidelines and reflects on two very different futures for humanity that may emerge from supporting or rejecting chimeric xenotransplantation.
• dc.description.sponsorship Spanish Ministry of Economy, Industry and Competitiveness, Retos DER2013-48066-C2-2-R.
• dc.format.mimetype application/pdf
• dc.identifier.citation Casal P, Williams A. Human iPSC-Chimera xenotransplantation and the non-identity problem. J Clin Med. 2019 Jan;8(1):95. DOI: 10.3390/jcm8010095
• dc.identifier.doi http://dx.doi.org/10.3390/jcm8010095
• dc.identifier.issn 2077-0383
• dc.identifier.uri http://hdl.handle.net/10230/55400
• dc.language.iso eng
• dc.publisher MDPI
• dc.relation.ispartof Journal of Clinical Medicine. 2019 Jan;8(1):95
• dc.relation.projectID info:eu-repo/grantAgreement/ES/1PE/DER2013-48066-C2-2-R
• dc.rights © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
• dc.rights.accessRights info:eu-repo/semantics/openAccess
• dc.rights.uri http://creativecommons.org/licenses/by/4.0/
• dc.subject.keyword Chimeric pigs
• dc.subject.keyword Chimpanzees
• dc.subject.keyword CRISPR
• dc.subject.keyword Ethics
• dc.subject.keyword Non-identity problem
• dc.subject.keyword Nonhuman person
• dc.subject.keyword Xenotourism
• dc.subject.keyword Xenotransplantation
• dc.subject.keyword Zoonotic risks
• dc.title Human iPSC-Chimera xenotransplantation and the non-identity problem
• dc.type info:eu-repo/semantics/article
• dc.type.version info:eu-repo/semantics/publishedVersion