• Understanding RanGTP dependent microtubule assembly : Idenification of DnaJB6 as a RanGTP regulated factor involved in microtubule organization during mitosis

  Rosas Salvans, Miquel, 1987- (Universitat Pompeu Fabra, 2017-12-19)

  Three microtubule (MT) assembly pathways participate in the assembly of the bipolar spindle: the centrosomal pathway, the augmin dependent amplification pathway and the RanGTP/chromosome dependent pathway. To form the ...
• Methyltransferase inhibitors interfere with Snail1 action on myofibroblast activity to prevent fibrosis and metastasis

  Sala Romanyà, Laura, 1989- (Universitat Pompeu Fabra, 2018-06-20)

  Snail1 is a transcription factor which activity is required for the fibroblasts-to-myofibroblast differentiation. In the first part of the thesis we characterize a protein complex involving Snail1, PRMT1 and PRMT4, two ...
• Spindle assembly and the control of microtubule nucleation through NEDD1 phosphorylation

  Timón Pérez, Krystal, 1987- (Universitat Pompeu Fabra, 2018-12-18)

  During mitosis, the microtubules organize a bipolar spindle that segregates the chromosomes. In higher eukaryotes, these microtubules are nucleated through three different pathways involving the centrosomes (centrosomal ...
• 'Making the most of it': the emergence, maintenance, and legitimation of the contemporary Northern Irish republican armed struggle

  Uležić, Sanjin (Universitat Pompeu Fabra, 2017-12-12)

  La tesi es centra en l'actual interació de la lluita armada republicana a Irlanda del Nord, activa des de l'època del procés de pau a finals dels anys noranta. Tot i caracteritzar-se per una intensitat menor que la del ...
• Essays on economic uncertainty

  Soupre, Matthieu (Universitat Pompeu Fabra, 2018-11-12)

  These essays propose different measures of economic uncertainty and evaluate its impact at the microeconomic and macroeconomic level. The first essay in Chapter 2 proposes a measure of macroeconomic uncertainty that allows ...
• La Traducción de valores socioculturales del español al chino en textos económicos: el caso del envasado de productos alimentarios

  Chen, Zhengyang (Universitat Pompeu Fabra, 2019-04-29)

  Que un producto español pueda insertarse exitosamente en el contexto chino depende principalmente de que el destinatario chino comprenda y valore positivamente ese producto. Para ello, la traducción de textos económicos ...
• An Object-oriented metamodel for digital signal processing with a focus on audio and music

  Amatriain, Xavier (Universitat Pompeu Fabra, 2005-01-27)

  Classical models for information transmission such as Shannon and Weaver's still tend to be looked at as the only possible scenarios where signal processing applications can be formally modeled. Meanwhile, other disciplines ...
• Three essays on the housing market and the macroeconomy

  Huber, Stefanie J. (Universitat Pompeu Fabra, 2017-06-15)

  This thesis sheds light on certain macroeconomic aspects of the housing market. Chapter 1 explores a novel channel for house price bubble formation: the demand for housing consumption. I argue that the lower the demand for ...
• Human-centered learning design with technology

  Garreta Domingo, Muriel (Universitat Pompeu Fabra, 2018-07-25)

  To improve and innovate education, a novel conception of the role of design in this realm is needed. Human-centered design (HCD), a problem-solving framework underpinned by the user perspective in all stages of the process, ...
• Native American genetic history through admixed populations of Brazil

  Mas Sandoval, Àlex, 1989- (Universitat Pompeu Fabra, 2018-11-30)

  Most of the Native American populations that lived in nowadays Eastern Brazil when the Europeans established in the area in the 16th century do not exist anymore. The colonization of Brazil implied huge migrations from ...
• Ligand selectivity at GPCRs: from multitarget binding profiles to biased agonism

  Martí Solano, Maria (Universitat Pompeu Fabra, 2015-02-10)

  La caracterització de diversos fàrmacs capaços d’unir-se a receptors associats a proteïnes G (GPCR)s ha revelat que els seus mecanismes d’acció no eren tan simples com es creia. Primer, l’anàlisi de la seva afinitat d’unió ...
• The Return to capital: new facts and interpretation

  Faltermeier, Julia (Universitat Pompeu Fabra, 2019-05-02)

  This thesis presents new facts on the aggregate return to capital and shows their implications for underlying drivers of investment and the efficiency of the alloca-tion of capital. The first chapter analyzes aggregate ...
• Native Italians' comprehension of press information in Spanish: a phraseodidactic approximation from a cognitive linguistics approach

  Mellado Blanes, Ester (Universitat Pompeu Fabra, 2019-04-26)

  This thesis analyses the interlanguage effect in the learning process of Spanish phraseology by native Italians. It is intended to investigate the interactions between native languages and the learning process of a foreign ...
• Television dialogue and subtitling: a corpus-driven study of police procedurals

  Arias Badia, Blanca (Universitat Pompeu Fabra, 2017-07-10)

  The specialised literature has suggested the intermediate position of television dialogue and subtitling along the continuum from spoken to written language (e.g. Díaz-Cintas 2003; Quaglio 2009; Forchini 2012). This ...
• Collective phenomena in networks of spiking neurons with synaptic delays

  Devalle, Federico (Universitat Pompeu Fabra, 2019-05-03)

  A prominent feature of the dynamics of large neuronal networks are the synchrony-driven collective oscillations generated by the interplay between synaptic coupling and synaptic delays. This thesis investigates the emergence ...
• Notch signalling in intestinal homeostasis and cancer: orchestrator of stemness

  López Arribillaga, Erika, 1986- (Universitat Pompeu Fabra, 2016-06-17)

  Wnt/β-catenin and Notch signalling cooperate in regulating the transcription of various genes specifically in the small intestinal stem and progenitor cell compartments. We characterized Bmi1 functionally in this context ...
• Identification of the sphingolipid desaturase DEGS1 as a novel gene for a leukodystrophy in therapeutic hope

  Pant, Devesh Chandra, 1987- (Universitat Pompeu Fabra, 2018-10-05)

  In spite of recent advances in understanding the genetic bases of leukodystrophies, a large number of clinical cases remain unexplained, suggesting that many leukodystrophy-associated genes have yet to be identified. Here ...
• Latin-American interculturalism: a multicultural model of education for Mexico

  Avena Koenigsberger, Alexandra Danielle (Universitat Pompeu Fabra, 2018-11-30)

  This thesis analyses whether multiculturalism is an adequate framework in order to advance in ethnocultural justice in the Latin American region, with a special focus on Mexico. Simultaneously, it analyses whether the claim ...
• Nation building in contested states

  Potapkina, Viktoria (Universitat Pompeu Fabra, 2019-02-27)

  This thesis provides an overview of current nation building processes in contested states. With a specific focus on the Turkish Republic of Northern Cyprus, Pridnestrovian Moldavian Republic, and Kosovo, original data is ...
• El Uso de medios sociales como fuente de información en periodismo internacional: cadenas globales de televisión en la cobertura de conflictos protagonizados por movientos sociales (2011-2017)

  Elena Muiña, Martin (Universitat Pompeu Fabra, 2018-12-03)

  La presente tesis tiene como objetivo investigar el uso de los medios sociales cuando son utilizados como fuente de información en tres de las principales cadenas de televisión de noticias globales, como son BBC World News, ...

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