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TDX
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Tesis doctorals llegides a la UPF en format digital en accés obert introduïdes a la plataforma TDX (Tesis Doctorals en Xarxa), on també es poden consultar tesis d'altres centres.
Enviaments recents
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(Universitat Pompeu Fabra, 2016-09-16)This Thesis aims at addressing the therapeutic potential of a neuroplasticity-targeted treatment for intellectual disability (ID) in Down syndrome (DS). The therapy consisted of the administration of the green tea catechin ...
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(Universitat Pompeu Fabra, 2017-01-18)Homotypic and heterotypic cell-cell fusion are key processes during development and tissue regeneration. On the other hand, aberrant heterotypic cell fusion between cancer and normal cells can contribute to tumor initiation ...
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(Universitat Pompeu Fabra, 2016-11-16)Human genomes have been found to harbor an unexpected number of ~100 loss-of-function (LoF) variants, with ~20 of them in an homozygous state, in most cases without a visible effect despite its potential truncation of ...
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(Universitat Pompeu Fabra, 2017-01-12)In this PhD I have used NGS technologies in different organisms and scenarios such as in ENCODE, comparing the conservation and evolution of long non-coding RNA sequences between human and mouse, using experimental evidences ...
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(Universitat Pompeu Fabra, 2017-01-13)Epithelial tissues undergo extensive remodeling during embryonic development. Recent studies have revealed that, in a number of developmental processes, epithelial remodeling is associated with pulsations of individual ...
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(Universitat Pompeu Fabra, 2017-01-13)Proteins are involved in almost all cell processes, with physical interaction between them being key to their function and dictated by its 3D structure. Hence, the study of protein-protein interactions and protein-protein ...
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(Universitat Pompeu Fabra, 2017-01-12)Tradicionalment considerat com un intèrpret d’obres alienes o com un instrument a mans del director, l’actor no ha estat contemplat en la historiografia del cinema ni en els discursos essencials que articulen la teoria ...
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(Universitat Pompeu Fabra, 2016-12-15)New high-throughput behavioral systems enable the recording of continuous behavioral sequences with an unprecedented richness of signals and a deep temporal resolution. Automated systems offer neuroscience the opportunity ...
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(Universitat Pompeu Fabra, 2018-05-18)La protection des minorités en Europe est le résultat d’une construction empirique qui trouve ses origines avec la Réforme, avant que les garanties religieuses ne se déplacent au XIXe siècle vers un curseur national. Cette ...
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(Universitat Pompeu Fabra, 2017-12-19)Targeted therapies against the Epidermal Growth Factor Receptor (EGFR) are useful to treat many human cancers such as non-small cell lung cancer, colorectal cancer and head and neck cancer. However, the efficacy of such ...
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(Universitat Pompeu Fabra, 2016-12-18)Epithelial tissues undergo extensive remodeling during embryonic development. Recent studies have revealed that, in a number of developmental processes, epithelial remodeling is associated with pulsations of individual ...
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(Universitat Pompeu Fabra, 2016-12-21)Tras la infección por VIH-1, el establecimiento de un depósito de células T en reposo infectadas latentemente con VIH impide la erradicación del virus en pacientes. Para lograr la erradicación, la terapia retroviral existente ...
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(Universitat Pompeu Fabra, 2016-11-28)The adenosinergic system is a neuromodulatory complex acting on four receptor subtypes with varying distributions throughout the central nervous system. This system contributes to homeostasis and regulates several physiological ...
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(Universitat Pompeu Fabra, 2014-12-19)We recently identified a novel cyclin called Cyclin O which is able to bind and activate Cdk1 and Cdk2 in response to intrinsic apoptotic stimuli like DNA damage or ER stress. Cyclin O has been shown to be involved in the ...
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(Universitat Pompeu Fabra, 2016-05-20)This thesis evaluates whether the increasing socioeconomic resources of women and men and the distribution of work within the couple have an effect on union instability. On the one hand, it assesses each spouse’s satisfaction ...
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(Universitat Pompeu Fabra, 2016-12-19)Gene dosage alterations of the kinase DYRK1A are linked to disease in humans. To better understand DYRK1A activities an interactome analysis was performed. RNF169, an E3-ubiquitin ligase key component of the cellular ...
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(Universitat Pompeu Fabra, 2015-12-05)The current doctoral thesis aims to know which individual and contextual factors determine risky alcohol consumption among adolescents, and concretely, to study the differences of consumption between rural and urban areas ...
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(Universitat Pompeu Fabra, 2016-12-16)Most of the cellular functions are driven by small-molecules that selectively bind to their protein targets. Is such their importance, that the pharmacological intervention of proteins by small molecule drugs is frequently ...
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(Universitat Pompeu Fabra, 2018-05-09)Planning in robotics is often split into task and motion planning. The task planner decides what needs to be done, while the motion planner fills up geometric details. However, such a decomposition is not effective in general ...
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(Universitat Pompeu Fabra, 2016-12-16)Rearrangements involving the mixed lineage leukemia gene (MLL) are found in majority of human infant leukemias (>60% of ALLs, 35% of AMLs) and are associated with dismal prognosis of these patients. They are also found in ...
