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TDX
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Tesis doctorals llegides a la UPF en format digital en accés obert introduïdes a la plataforma TDX (Tesis Doctorals en Xarxa), on també es poden consultar tesis d'altres centres.
Recent Submissions
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(Universitat Pompeu Fabra, 2010-12-20)Carbohydrate-binding proteins of non-immunological origin -lectins- have been recognized over the last decades as decisive players in numerous biological processes, ranging from cellcell communication, fertilization, ...
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(Universitat Pompeu Fabra, 2009-09-10)In the intestinal epithelium, Wnt signaling drives the expression of the genes encoding tyrosine kinase receptors EphB2 and EphB3 and represses the expression of their membrane-tethered ligands, ephrin-Bs. Eph-ephrin ...
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(Universitat Pompeu Fabra, 2010-07-05)Les cèl·lules mare embrionàries humanes (hESC) i més recentment les cèl·lules de pluripotència induïda (iPSC) representen una oportunitat sense precedents per al desenvolupament de noves estratègies terapèutiques per ...
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(Universitat Pompeu Fabra, 2009-02-20)This work is centered on the study of the NKG2 C-type lectin-like receptors on NK and CD4+T cells. We provide evidence supporting that CD4+T cells specific for Human Cytomegalovirus (HCMV) may express different NK cell ...
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(Universitat Pompeu Fabra, 2010-06-22)Classically it was assumed that the compounds with therapeutic effect exert their action interacting with a single receptor. Nowadays it is widely recognized that the pharmacological effect of most drugs is more complex ...
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(Universitat Pompeu Fabra, 2008-12-19)Les duplicacions segmentàries (DSs), o també anomenades duplicons o Low copy Repeats (LCRs), són regions de coma mínim 1 kb amb un alt nivell d'identitat (>90%), que estan presents almenys dues vegades en el genoma. La ...
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(Universitat Pompeu Fabra, 2008-07-24)La neteja del moc i dels patògens dels pulmons, i el transport de gàmets i embrions en els òrgans reproductius de les femelles són funcions clau en els epitelis ciliats, tals com aquells que es troben presents en les vies ...
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(Universitat Pompeu Fabra, 2008-12-18)El gen DYRK1A es troba situat en una regió del cromosoma 21 humà que s'ha associat a alteracions en el neurodesenvolupament. Aquest treball mostra com canvis en la dosis gènica de Dyrk1A en el ratolí causen una alteració ...
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(Universitat Pompeu Fabra, 2008-01-28)La presente tesis "Modelling of 5-HT2A and 5-HT2C receptors and of their complexes with actual and potential antipsychotic drugs" tiene como objetivo de profundizar los conocimientos actuales sobre el mecanismo de acción ...
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(Universitat Pompeu Fabra, 2010-03-04)The work of this thesis was focused on the development of high-performance algorithms for a new generation of molecular descriptors, with many advantages with respect to its predecessors, suitable for diverse applications ...
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(Universitat Pompeu Fabra, 2010-04-09)Ptf1a/p48 is a pancreas specific bHLH transcription factor that is required at early stages of embryonic development for pancreas formation and, during adulthood, for the proper exocrine pancreatic function. P48 also exerts ...
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(Universitat Pompeu Fabra, 2010-12-17)17β-nandrolone (17βN) is illegally used in sport and in livestock as a growth promoter.17βN and some of their metabolites have been described as endogenous compounds in some animals, such as adult boars and entire male ...
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(Universitat Pompeu Fabra, 2004-06-28)Los agentes anabolizantes prohibidos por la Comisión Médica del Comité Olímpico Internacional (COI) deben estar ausentes en las muestras de orina objeto de análisis. El límite de detección está condicionado por la ...
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(Universitat Pompeu Fabra, 2011-12-12)Múltiples revisiones científicas han intentado determinar los factores pronósticos en la evolución del latigazo cervical sin llegar a un consenso. Nuestros resultados se han obtenido tras 8 años de estudio en pacientes controlados ...
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(Universitat Pompeu Fabra, 2016-11-28)Current biomedical research needs to leverage the large amount of information reported in scientific publications. Automated text processing, commonly known as text mining, has become an indispensable tool to identify, ...
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(Universitat Pompeu Fabra, 2008-04-21)PURPOSE: To determine the management performance indicators most frequently utilized in academic radiology departments in the United States. MATERIALS AND METHODS: This investigation met the criteria for an exemption from ...
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(Universitat Pompeu Fabra, 2010-11-24)The c-Myc transcription factor is a key player in cell homeostasis, being commonly deregulated in human carcinogenesis. In this PhD thesis we have addressed the question how regulatory mechanisms restrain the oncogenic ...
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(Universitat Pompeu Fabra, 2010-03-26)The informational content of 3' splice sites is low and the mechanisms whereby they are selected are not clear. Here we enunciate a set of rules that govern their selection. For many introns, secondary structures are a key ...
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(Universitat Pompeu Fabra, 2008-06-20)The product of the snail1 gene (SNAIL1) is a transcriptional repressor required for triggering the epithelial-to-mesenchymal transition (EMT). SNAIL1 transcription is induced when epithelial cells are forced to acquire a ...
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(Universitat Pompeu Fabra, 2011-11-25)La incapacidad temporal por contingencia común (ITcc) representa un elevado coste social. Cualquier esfuerzo para desarrollar políticas orientadas a mejorar la gestión de los episodios de ITcc y facilitar el retorno al ...
