• Bridging LGBT+ content gaps across Wikipedia language editions

  Miquel Ribé, Marc; Kaltenbrunner, Andreas; Keefer, Jeffrey M. (University of Toronto, 2021)

  In the past several years, the Wikimedia Movement has become more aware of the lack of representation of specific communities, that is, content gaps. Next to geographical and gender-related initiatives, the LGBT+ Wikimedia ...
• The ideology of media: measuring the political leaning of Spanish news media through Twitter users’ interactions

  Guerrero Solé, Frederic (Universidad de Navarra, 2022)

  The news media have a strong influence on people’s perception of reality. But despite claims to objectivity, media organizations are, in general, politically biased (Patterson & Donsbach, 1996; Gaebler, 2017). The link ...
• Calidad web en medios digitales: revisión bibliográfica sobre métodos e indicadores de evaluación general y atributos de confianza

  Morales-Vargas, Alejandro; Pedraza, Rafael; Codina, Lluís (Universidad de La Laguna, 2022)

  Introduction: In the context of the loss of confidence towards Internet content, misinformation, fakenewsandthefinancialcrisisaffectingthepressglobally,thestudiesthatproposeinstrumentsdedicated to evaluating digital ...
• Website quality in digital media: literature reviewon general evaluation methods and indicators and reliability attributes

  Morales-Vargas, Alejandro; Pedraza, Rafael; Codina, Lluís (Universidad de La Laguna, 2022)

  Introducción: Frente a la pérdida de confianza hacia los contenidos en internet, la desinformación, las noticias falsas y la crisis financiera que afecta a la prensa a nivel global, se revisan los estudios que proponen ...
• Perceived credibility of tweets by opinion leaders during the COVID-19 pandemic in Spain

  Besalú Casademont, Reinald; Pont Sorribes, Carles; Martí, Aleix (University of Southern California, Annenberg School for Communication & Journalism, 2021)

  The informational practices of citizens, transformed by the digital sphere, pose new challenges such as misinformation and disinformation, and they also require a rethinking of the role of opinion leaders. We explored how, ...
• Role of cannabinoids in alcohol-induced neuroinflammation

  García Baos, Alba; Alegre Zurano, Laia; Cantacorps Centellas, Lídia, 1991-; Martín Sánchez, Ana; Valverde Granados, Olga (Elsevier, 2021)

  Alcohol is a psychoactive substance highly used worldwide, whose harmful use might cause a broad range of mental and behavioural disorders. Underlying brain impact, the neuroinflammatory response induced by alcohol is ...
• STAG2 loss-of-function affects short-range genomic contacts and modulates the basal-luminal transcriptional program of bladder cancer cells

  Richart, Laia; Lapi, Eleonora; Pancaldi, Vera; Cuenca-Ardura, Mirabai; Carrillo-de-Santa Pau, Enrique; Madrid-Mencía, Miguel; Neyret-Kahn, Hélène; Radvanyi, François; Rodríguez, Juan Antonio; Cuartero, Yasmina; Serra, François; Le Dily, François; Valencia, Alfonso; Martí Renom, Marc A.; Real, Francisco X. (Oxford University Press, 2021)

  Cohesin exists in two variants containing STAG1 or STAG2. STAG2 is one of the most mutated genes in cancer and a major bladder tumor suppressor. Little is known about how its inactivation contributes to tumorigenesis. Here, ...
• Find and cut-and-transfer (FiCAT) mammalian genome engineering

  Pallarès-Masmitjà, Maria; Ivančić, Dimitrije; Mir-Pedrol, Júlia; Jaraba-Wallace, Jessica; Tagliani, Tommaso; Oliva Miguel, Baldomero; Rahmeh, Amal; Sánchez-Mejías, Avencia; Güell Cargol, Marc (Nature Research, 2021)

  While multiple technologies for small allele genome editing exist, robust technologies for targeted integration of large DNA fragments in mammalian genomes are still missing. Here we develop a gene delivery tool (FiCAT) ...
• Entrectinib-A SARS-CoV-2 inhibitor in Human Lung Tissue (HLT) cells

  Peralta-Garcia, Alejandro; Torrens Fontanals, Mariona; Stepniewski, Tomasz Maciej, 1988-; Grau-Expósito, Judith; Perea, David; Ayinampudi, Vikram; Waldhoer, Maria; Zimmermann, Mirjam; Buzón, María J.; Genescà, Meritxell; Selent, Jana (MDPI, 2021)

  Since the start of the COVID-19 outbreak, pharmaceutical companies and research groups have focused on the development of vaccines and antiviral drugs against SARS-CoV-2. Here, we apply a drug repurposing strategy to ...
• Long-term evolution of the adaptive NKG2C + NK cell response to cytomegalovirus infection in kidney transplantation: an insight on the diversity of host-pathogen interaction

  Ataya Fernández, Michelle, 1993-; Redondo Pachón, María Dolores; Llinàs-Mallol, Laura; Yélamos López, José; Alari-Pahissa, Elisenda; Pérez-Sáez, María José; Altadill, Mireia; Raïch-Regué, Dàlia; Vilches, Carlos; Pascual Santos, Julio; Crespo Barrio, Marta; López-Botet, Miguel (American Association of Immunologists - AAI, 2021)

  Human CMV infection is frequent in kidney transplant recipients (KTR). Pretransplant Ag-specific T cells and adaptive NKG2C+ NK cells associate with reduced incidence of infection in CMV+ KTR. Expansions of adaptive NKG2C+ ...
• Lifestyle and behavioral factors and mitochondrial DNA copy number in a diverse cohort of mid-life and older adults

  Vyas, Chirag M.; Ogata, Soshiro; Reynolds, Charles F. 3rd; Mischoulon, David; Chang, Grace; Cook, Nancy R.; Manson, JoAnn E.; Crous-Bou, Marta; De Vivo, Immaculata; Okereke, Olivia I. (Public Library of Science (PLoS), 2020)

  Mitochondrial DNA copy number (mtDNAcn) is a putative biomarker of oxidative stress and biological aging. Modifiable factors, including physical activity (PA), avoidance of heavy alcohol use and smoking, and maintaining ...
• NOX5-induced uncoupling of endothelial NO synthase is a causal mechanism and theragnostic target of an age-related hypertension endotype

  Elbatreek, Mahmoud; Sadegh, Sepideh; Anastasi, Elisa; Guney, Emre; Nogales, Cristian; Kacprowski, Tim; Hassan, Ahmed; Teubner, Andreas; Huang, Po-Hsun; Hsu, Chien-Yi; Schiffers, Paul M. H.; Janssen, Ger M.; Kleikers, Pamela W.M.; Wipat, Anil; Baumbach, Jan; De Mey, Jo G.R.; Schmidt, Harald H.H.W. (Public Library of Science (PLoS), 2020)

  Hypertension is the most important cause of death and disability in the elderly. In 9 out of 10 cases, the molecular cause, however, is unknown. One mechanistic hypothesis involves impaired endothelium-dependent vasodilation ...
• Validation and clinical application of a targeted next-generation sequencing gene panel for solid and hematologic malignancies

  Prieto-Potin, Iván; Carvajal, Nerea; Plaza-Sánchez, Jenifer; Manso, Rebeca; Aúz-Alexandre, Carmen Laura; Chamizo, Cristina; Zazo, Sandra; López-Sánchez, Almudena; Rodríguez-Pinilla, Socorro María; Camacho Díaz, Laura; Longarón Rozalen, Raquel; Bellosillo Paricio, Beatriz; Somoza, Rosa; Hernández-Losa, Javier; Fernández-Soria, Víctor Manuel; Ramos-Ruiz, Ricardo; Cristóbal, Ion; García-Foncillas, Jesús; Rojo, Federico (PeerJ Inc., 2020)

  Background: Next-generation sequencing (NGS) is a high-throughput technology that has become widely integrated in molecular diagnostics laboratories. Among the large diversity of NGS-based panels, the Trusight Tumor 26 ...
• Male and female politicians on twitter: a machine learning approach

  Beltran, Javier; Gallego Dobón, Aina; Huidobro, Alba; Romero Merino, Enrique; Padró, Lluís (Wiley, 2021)

  How does the language of male and female politicians differ when they communicate directly with the public on social media? Do citizens address them differently? We apply Lasso logistic regression models to identify the ...
• Population history of North Africa based on modern and ancient genomes

  Lucas-Sánchez, Marcel; Serradell, Jose M.; Comas, David, 1969- (Oxford University Press, 2021)

  Compared with the rest of the African continent, North Africa has provided limited genomic data. Nonetheless, the genetic data available show a complex demographic scenario characterized by extensive admixture and drift. ...
• The landscape of somatic mutation in cerebral cortex of autistic and neurotypical individuals revealed by ultra-deep whole-genome sequencing

  Rodin, Rachel E.; Brain Somatic Mosaicism Network; Walsh, Christopher A. (Nature Research, 2021)

  We characterize the landscape of somatic mutations-mutations occurring after fertilization-in the human brain using ultra-deep (~250×) whole-genome sequencing of prefrontal cortex from 59 donors with autism spectrum disorder ...
• Maximizing the acquisition of unique reads in noninvasive capture sequencing experiments

  Fontseré Alemany, Clàudia, 1992-; Alvarez-Estape, Marina; Kuhlwilm, Martin; Marquès i Bonet, Tomàs, 1975-; Lizano González, Esther, 1974- (Wiley, 2021)

  Noninvasive samples as a source of DNA are gaining interest in genomic studies of endangered species. However, their complex nature and low endogenous DNA content hamper the recovery of good quality data. Target capture ...
• The dental proteome of Homo antecessor

  Welker, Frido; Chiva, Cristina; Kuhlwilm, Martin; Manuel Montero, Marc de, 1991-; Gelabert Xirinachs, Pere, 1991-; Marquès i Bonet, Tomàs, 1975-; Sabidó Aguadé, Eduard, 1981-; Lalueza Fox, Carles, 1965-; Cappellini, Enrico (Nature Research, 2020)

  The phylogenetic relationships between hominins of the Early Pleistocene epoch in Eurasia, such as Homo antecessor, and hominins that appear later in the fossil record during the Middle Pleistocene epoch, such as Homo ...
• Identification of risk features for complication in Gaucher's disease patients: a machine learning analysis of the Spanish registry of Gaucher disease

  Andrade-Campos, Marcio; López de Frutos, Laura; Cebolla, Jorge J.; Serrano-Gonzalo, Irene; Medrano-Engay, Blanca; Roca-Espiau, Mercedes; Gómez-Barrera, Beatriz; Pérez-Heredia, Jorge; Iniguez, David; Giraldo, Pilar (BioMed Central, 2020)

  Background: Since enzyme replacement therapy for Gaucher disease (MIM#230800) has become available, both awareness of and the natural history of the disease have changed. However, there remain unmet needs such as the ...
• Benefit of primary percutaneous coronary interventions in the elderly with ST segment elevation myocardial infarction

  Fernández-Bergés, Daniel; Dégano, Irene R.; Subirana Cachinero, Isaac; Martí-Almor, Julio; Vila, Joan; Pérez-Fernández, Silvia; Martí-Almor, Julio; Elosua Llanos, Roberto; Marrugat de la Iglesia, Jaume; ATHOS investigators (BMJ Publishing Group, 2020)

  Objective: Primary percutaneous coronary intervention (P-PCI) has demonstrated its efficacy in patients with ST segment elevation myocardial infarction (STEMI). However, patients with STEMI ≥75 years receive less P-PCI ...

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