Cardiovascular benefits of moderate exercise training in Marfan syndrome: insights from an animal model

Mas‐Stachurska, Aleksandra; Siegert, Anna‐Maria; Batlle, Montserrat; Gorbenko del Blanco, Darya; Meirelles, Thayna; Rubies, Cira; Bonorino, Fabio; Serra‐Peinado, Carla; Bijnens, Bart; Baudin, Julio; Sitges, Marta; Mont, Lluís; Guasch, Eduard; Egea, Gustavo

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dc.contributor.author	Mas‐Stachurska, Aleksandra
dc.contributor.author	Siegert, Anna‐Maria
dc.contributor.author	Batlle, Montserrat
dc.contributor.author	Gorbenko del Blanco, Darya
dc.contributor.author	Meirelles, Thayna
dc.contributor.author	Rubies, Cira
dc.contributor.author	Bonorino, Fabio
dc.contributor.author	Serra‐Peinado, Carla
dc.contributor.author	Bijnens, Bart
dc.contributor.author	Baudin, Julio
dc.contributor.author	Sitges, Marta
dc.contributor.author	Mont, Lluís
dc.contributor.author	Guasch, Eduard
dc.contributor.author	Egea, Gustavo
dc.date.accessioned	2019-03-25T09:51:44Z
dc.date.available	2019-03-25T09:51:44Z
dc.date.issued	2017
dc.identifier.citation	Mas‐Stachurska A, Siegert AM, Batlle M, Gorbenko del Blanco D, Meirelles T, Rubies C, Bonorino F, Serra‐Peinado C, Baudin J, Sitges M, Mont L, Guasch E, Egea G. Cardiovascular benefits of moderate exercise training in Marfan syndrome: insights from an animal model. J Am Heart Assoc. 2017;6(9):e006438. DOI: 10.1161/JAHA.117.006438
dc.identifier.issn	2047-9980
dc.identifier.uri	http://hdl.handle.net/10230/36956
dc.description.abstract	Marfan syndrome (MF) leads to aortic root dilatation and a predisposition to aortic dissection, mitral valve prolapse, and primary and secondary cardiomyopathy. Overall, regular physical exercise is recommended for a healthy lifestyle, but dynamic sports are strongly discouraged in MF patients. Nonetheless, evidence supporting this recommendation is lacking. Therefore, we studied the role of long‐term dynamic exercise of moderate intensity on the MF cardiovascular phenotype.
dc.description.sponsorship	This work was partially supported by grants from the Instituto de Salud Carlos III (PI13/01580, PI16/00703); Sociedad Española de Cardiología; National Marfan Foundation; Ministerio de Economia y Competitividad (SAF2015‐64136R, SAF2017‐83039‐R, TIN2014‐52923‐R); Fondo Europeo de Desarrollo Regional (FEDER); Agència de Gestió d'Ajuts Universitaris i de Recerca (2014SGR334); CERCA Programme/Generalitat de Catalunya and Centro de Investigación Biomédica en RED (CIBERCV 16/11/00354).
dc.format.mimetype	application/pdf
dc.language.iso	eng
dc.publisher	Wiley
dc.relation.ispartof	Journal of the American Heart Association. 2017;6(9):e006438
dc.rights	© 2017 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is noncommercial and no modifications or adaptations are made.
dc.rights.uri	https://creativecommons.org/licenses/by-nc-nd/4.0/
dc.title	Cardiovascular benefits of moderate exercise training in Marfan syndrome: insights from an animal model
dc.type	info:eu-repo/semantics/article
dc.identifier.doi	http://dx.doi.org/10.1161/JAHA.117.006438
dc.subject.keyword	Vascular disease
dc.subject.keyword	Exercise
dc.subject.keyword	Aneurysm
dc.subject.keyword	Behavioral medicine
dc.subject.keyword	Prevention
dc.subject.keyword	Basic
dc.subject.keyword	Epidemiology
dc.subject.keyword	Health
dc.subject.keyword	Wellness
dc.subject.keyword	Translational
dc.subject.keyword	Clinical research
dc.subject.keyword	Lifestyle
dc.subject.keyword	Prevention
dc.subject.keyword	Animal models
dc.subject.keyword	Human disease
dc.relation.projectID	info:eu-repo/grantAgreement/ES/1PE/SAF2015‐64136R
dc.relation.projectID	info:eu-repo/grantAgreement/ES/2PE/SAF2017‐83039‐R
dc.relation.projectID	info:eu-repo/grantAgreement/ES/1PE/TIN2014‐52923‐R
dc.rights.accessRights	info:eu-repo/semantics/openAccess
dc.type.version	info:eu-repo/semantics/publishedVersion