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Cardiovascular benefits of moderate exercise training in Marfan syndrome: insights from an animal model

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dc.contributor.author Mas‐Stachurska, Aleksandra
dc.contributor.author Siegert, Anna‐Maria
dc.contributor.author Batlle, Montserrat
dc.contributor.author Gorbenko del Blanco, Darya
dc.contributor.author Meirelles, Thayna
dc.contributor.author Rubies, Cira
dc.contributor.author Bonorino, Fabio
dc.contributor.author Serra‐Peinado, Carla
dc.contributor.author Bijnens, Bart
dc.contributor.author Baudin, Julio
dc.contributor.author Sitges, Marta
dc.contributor.author Mont, Lluís
dc.contributor.author Guasch, Eduard
dc.contributor.author Egea, Gustavo
dc.date.accessioned 2019-03-25T09:51:44Z
dc.date.available 2019-03-25T09:51:44Z
dc.date.issued 2017
dc.identifier.citation Mas‐Stachurska A, Siegert AM, Batlle M, Gorbenko del Blanco D, Meirelles T, Rubies C, Bonorino F, Serra‐Peinado C, Baudin J, Sitges M, Mont L, Guasch E, Egea G. Cardiovascular benefits of moderate exercise training in Marfan syndrome: insights from an animal model. J Am Heart Assoc. 2017;6(9):e006438. DOI: 10.1161/JAHA.117.006438
dc.identifier.issn 2047-9980
dc.identifier.uri http://hdl.handle.net/10230/36956
dc.description.abstract Marfan syndrome (MF) leads to aortic root dilatation and a predisposition to aortic dissection, mitral valve prolapse, and primary and secondary cardiomyopathy. Overall, regular physical exercise is recommended for a healthy lifestyle, but dynamic sports are strongly discouraged in MF patients. Nonetheless, evidence supporting this recommendation is lacking. Therefore, we studied the role of long‐term dynamic exercise of moderate intensity on the MF cardiovascular phenotype.
dc.description.sponsorship This work was partially supported by grants from the Instituto de Salud Carlos III (PI13/01580, PI16/00703); Sociedad Española de Cardiología; National Marfan Foundation; Ministerio de Economia y Competitividad (SAF2015‐64136R, SAF2017‐83039‐R, TIN2014‐52923‐R); Fondo Europeo de Desarrollo Regional (FEDER); Agència de Gestió d'Ajuts Universitaris i de Recerca (2014SGR334); CERCA Programme/Generalitat de Catalunya and Centro de Investigación Biomédica en RED (CIBERCV 16/11/00354).
dc.format.mimetype application/pdf
dc.language.iso eng
dc.publisher Wiley
dc.relation.ispartof Journal of the American Heart Association. 2017;6(9):e006438
dc.rights © 2017 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is noncommercial and no modifications or adaptations are made.
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/
dc.title Cardiovascular benefits of moderate exercise training in Marfan syndrome: insights from an animal model
dc.type info:eu-repo/semantics/article
dc.identifier.doi http://dx.doi.org/10.1161/JAHA.117.006438
dc.subject.keyword Vascular disease
dc.subject.keyword Exercise
dc.subject.keyword Aneurysm
dc.subject.keyword Behavioral medicine
dc.subject.keyword Prevention
dc.subject.keyword Basic
dc.subject.keyword Epidemiology
dc.subject.keyword Health
dc.subject.keyword Wellness
dc.subject.keyword Translational
dc.subject.keyword Clinical research
dc.subject.keyword Lifestyle
dc.subject.keyword Prevention
dc.subject.keyword Animal models
dc.subject.keyword Human disease
dc.relation.projectID info:eu-repo/grantAgreement/ES/1PE/SAF2015‐64136R
dc.relation.projectID info:eu-repo/grantAgreement/ES/2PE/SAF2017‐83039‐R
dc.relation.projectID info:eu-repo/grantAgreement/ES/1PE/TIN2014‐52923‐R
dc.rights.accessRights info:eu-repo/semantics/openAccess
dc.type.version info:eu-repo/semantics/publishedVersion

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