Cardiovascular benefits of moderate exercise training in Marfan syndrome: insights from an animal model

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  • dc.contributor.author Mas‐Stachurska, Aleksandra
  • dc.contributor.author Siegert, Anna‐Maria
  • dc.contributor.author Batlle, Montserrat
  • dc.contributor.author Gorbenko del Blanco, Darya
  • dc.contributor.author Meirelles, Thayna
  • dc.contributor.author Rubies, Cira
  • dc.contributor.author Bonorino, Fabio
  • dc.contributor.author Serra‐Peinado, Carla
  • dc.contributor.author Bijnens, Bart
  • dc.contributor.author Baudin, Julio
  • dc.contributor.author Sitges, Marta
  • dc.contributor.author Mont, Lluís
  • dc.contributor.author Guasch, Eduard
  • dc.contributor.author Egea, Gustavo
  • dc.date.accessioned 2019-03-25T09:51:44Z
  • dc.date.available 2019-03-25T09:51:44Z
  • dc.date.issued 2017
  • dc.description.abstract Marfan syndrome (MF) leads to aortic root dilatation and a predisposition to aortic dissection, mitral valve prolapse, and primary and secondary cardiomyopathy. Overall, regular physical exercise is recommended for a healthy lifestyle, but dynamic sports are strongly discouraged in MF patients. Nonetheless, evidence supporting this recommendation is lacking. Therefore, we studied the role of long‐term dynamic exercise of moderate intensity on the MF cardiovascular phenotype.
  • dc.description.sponsorship This work was partially supported by grants from the Instituto de Salud Carlos III (PI13/01580, PI16/00703); Sociedad Española de Cardiología; National Marfan Foundation; Ministerio de Economia y Competitividad (SAF2015‐64136R, SAF2017‐83039‐R, TIN2014‐52923‐R); Fondo Europeo de Desarrollo Regional (FEDER); Agència de Gestió d'Ajuts Universitaris i de Recerca (2014SGR334); CERCA Programme/Generalitat de Catalunya and Centro de Investigación Biomédica en RED (CIBERCV 16/11/00354).
  • dc.format.mimetype application/pdf
  • dc.identifier.citation Mas‐Stachurska A, Siegert AM, Batlle M, Gorbenko del Blanco D, Meirelles T, Rubies C, Bonorino F, Serra‐Peinado C, Baudin J, Sitges M, Mont L, Guasch E, Egea G. Cardiovascular benefits of moderate exercise training in Marfan syndrome: insights from an animal model. J Am Heart Assoc. 2017;6(9):e006438. DOI: 10.1161/JAHA.117.006438
  • dc.identifier.doi http://dx.doi.org/10.1161/JAHA.117.006438
  • dc.identifier.issn 2047-9980
  • dc.identifier.uri http://hdl.handle.net/10230/36956
  • dc.language.iso eng
  • dc.publisher Wiley
  • dc.relation.ispartof Journal of the American Heart Association. 2017;6(9):e006438
  • dc.relation.projectID info:eu-repo/grantAgreement/ES/1PE/SAF2015‐64136R
  • dc.relation.projectID info:eu-repo/grantAgreement/ES/2PE/SAF2017‐83039‐R
  • dc.relation.projectID info:eu-repo/grantAgreement/ES/1PE/TIN2014‐52923‐R
  • dc.rights © 2017 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is noncommercial and no modifications or adaptations are made.
  • dc.rights.accessRights info:eu-repo/semantics/openAccess
  • dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/
  • dc.subject.keyword Vascular disease
  • dc.subject.keyword Exercise
  • dc.subject.keyword Aneurysm
  • dc.subject.keyword Behavioral medicine
  • dc.subject.keyword Prevention
  • dc.subject.keyword Basic
  • dc.subject.keyword Epidemiology
  • dc.subject.keyword Health
  • dc.subject.keyword Wellness
  • dc.subject.keyword Translational
  • dc.subject.keyword Clinical research
  • dc.subject.keyword Lifestyle
  • dc.subject.keyword Prevention
  • dc.subject.keyword Animal models
  • dc.subject.keyword Human disease
  • dc.title Cardiovascular benefits of moderate exercise training in Marfan syndrome: insights from an animal model
  • dc.type info:eu-repo/semantics/article
  • dc.type.version info:eu-repo/semantics/publishedVersion