Cardiovascular benefits of moderate exercise training in Marfan syndrome: insights from an animal model
Cardiovascular benefits of moderate exercise training in Marfan syndrome: insights from an animal model
Citation
- Mas‐Stachurska A, Siegert AM, Batlle M, Gorbenko del Blanco D, Meirelles T, Rubies C, Bonorino F, Serra‐Peinado C, Baudin J, Sitges M, Mont L, Guasch E, Egea G. Cardiovascular benefits of moderate exercise training in Marfan syndrome: insights from an animal model. J Am Heart Assoc. 2017;6(9):e006438. DOI: 10.1161/JAHA.117.006438
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Abstract
Marfan syndrome (MF) leads to aortic root dilatation and a predisposition to aortic dissection, mitral valve prolapse, and primary and secondary cardiomyopathy. Overall, regular physical exercise is recommended for a healthy lifestyle, but dynamic sports are strongly discouraged in MF patients. Nonetheless, evidence supporting this recommendation is lacking. Therefore, we studied the role of long‐term dynamic exercise of moderate intensity on the MF cardiovascular phenotype.