Cardiovascular benefits of moderate exercise training in Marfan syndrome: insights from an animal model

Mas‐Stachurska, Aleksandra; Siegert, Anna‐Maria; Batlle, Montserrat; Gorbenko del Blanco, Darya; Meirelles, Thayna; Rubies, Cira; Bonorino, Fabio; Serra‐Peinado, Carla; Bijnens, Bart; Baudin, Julio; Sitges, Marta; Mont, Lluís; Guasch, Eduard; Egea, Gustavo

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Cardiovascular benefits of moderate exercise training in Marfan syndrome: insights from an animal model

Document Type: Article

Version: Published version

Date: 2017

This document is associated with a Creative Common license

© 2017 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is noncommercial and no modifications or adaptations are made.

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Citation: Mas‐Stachurska A, Siegert AM, Batlle M, Gorbenko del Blanco D, Meirelles T, Rubies C, Bonorino F, Serra‐Peinado C, Baudin J, Sitges M, Mont L, Guasch E, Egea G. Cardiovascular benefits of moderate exercise training in Marfan syndrome: insights from an animal model. J Am Heart Assoc. 2017;6(9):e006438. DOI: 10.1161/JAHA.117.006438

Permanent link: http://hdl.handle.net/10230/36956

Abstract:

Marfan syndrome (MF) leads to aortic root dilatation and a predisposition to aortic dissection, mitral valve prolapse, and primary and secondary cardiomyopathy. Overall, regular physical exercise is recommended for a healthy lifestyle, but dynamic sports are strongly discouraged in MF patients. Nonetheless, evidence supporting this recommendation is lacking. Therefore, we studied the role of long‐term dynamic exercise of moderate intensity on the MF cardiovascular phenotype.