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dc.contributor.author Gerstner, Wulfram
dc.contributor.author Sprekeler, Henning
dc.contributor.author Deco, Gustavo
dc.date.accessioned 2016-07-19T07:36:31Z
dc.date.available 2016-07-19T07:36:31Z
dc.date.issued 2012
dc.identifier.citation Gerstner W, Sprekeler H, Deco G. Theory and simulation in neuroscience. Science. 2012;338(6103):60-5. DOI: 10.1126/science.1227356
dc.identifier.issn 0036-8075
dc.identifier.uri http://hdl.handle.net/10230/27080
dc.description.abstract Modeling work in neuroscience can be classified using two different criteria. The first one is the complexity of the model, ranging from simplified conceptual models that are amenable to mathematical analysis to detailed models that require simulations in order to understand their properties. The second criterion is that of direction of workflow, which can be from microscopic to macroscopic scales (bottom-up) or from behavioral target functions to properties of components (top-down). We review the interaction of theory and simulation using examples of top-down and bottom-up studies and point to some current developments in the fields of computational and theoretical neuroscience.
dc.description.sponsorship Supported by European Research/nCouncil grants 268689 (W.G.) and 295129 (G.D.); the/nEuropean Community’s Seventh Framework Program/n(grant agreement 243914, Brain-I-Nets, W.G. and H.S.;/ngrant agreement 269921, BrainScaleS, W.G. and G.D.); Swiss/nNational Science Foundation grants 200020 and 132871;/nand Spanish Ministerio de Economia y Competitividad grants/nCDS-2007-00012 and SAF2010-16085. We thank T. Vogels/nfor helpful discussions.
dc.format.mimetype application/pdf
dc.language.iso eng
dc.publisher American Association for the Advancement of Science (AAAS)
dc.relation.ispartof Science. 2012;338(6103):60-5
dc.rights © American Association for the Advancement of Science (AAAS) http://dx.doi.org/10.1126/science.1227356
dc.title Theory and simulation in neuroscience
dc.type info:eu-repo/semantics/article
dc.identifier.doi http://dx.doi.org/10.1126/science.1227356
dc.relation.projectID info:eu-repo/grantAgreement/EC/FP7/295129
dc.relation.projectID info:eu-repo/grantAgreement/EC/FP7/268689
dc.relation.projectID info:eu-repo/grantAgreement/EC/FP7/243914
dc.relation.projectID info:eu-repo/grantAgreement/EC/FP7/269921
dc.relation.projectID info:eu-repo/grantAgreement/ES/2PN/CDS-2007-00012
dc.relation.projectID info:eu-repo/grantAgreement/ES/3PN/SAF2010-16085
dc.rights.accessRights info:eu-repo/semantics/openAccess
dc.type.version info:eu-repo/semantics/submittedVersion

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