Theory and simulation in neuroscience

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• dc.contributor.author Gerstner, Wulframca
• dc.contributor.author Sprekeler, Henningca
• dc.contributor.author Deco, Gustavoca
• dc.date.accessioned 2016-07-19T07:36:31Z
• dc.date.available 2016-07-19T07:36:31Z
• dc.date.issued 2012ca
• dc.description.abstract Modeling work in neuroscience can be classified using two different criteria. The first one is the complexity of the model, ranging from simplified conceptual models that are amenable to mathematical analysis to detailed models that require simulations in order to understand their properties. The second criterion is that of direction of workflow, which can be from microscopic to macroscopic scales (bottom-up) or from behavioral target functions to properties of components (top-down). We review the interaction of theory and simulation using examples of top-down and bottom-up studies and point to some current developments in the fields of computational and theoretical neuroscience.
• dc.description.sponsorship Supported by European Research/nCouncil grants 268689 (W.G.) and 295129 (G.D.); the/nEuropean Community’s Seventh Framework Program/n(grant agreement 243914, Brain-I-Nets, W.G. and H.S.;/ngrant agreement 269921, BrainScaleS, W.G. and G.D.); Swiss/nNational Science Foundation grants 200020 and 132871;/nand Spanish Ministerio de Economia y Competitividad grants/nCDS-2007-00012 and SAF2010-16085. We thank T. Vogels/nfor helpful discussions.
• dc.format.mimetype application/pdfca
• dc.identifier.citation Gerstner W, Sprekeler H, Deco G. Theory and simulation in neuroscience. Science. 2012;338(6103):60-5. DOI: 10.1126/science.1227356ca
• dc.identifier.doi http://dx.doi.org/10.1126/science.1227356
• dc.identifier.issn 0036-8075ca
• dc.identifier.uri http://hdl.handle.net/10230/27080
• dc.language.iso engca
• dc.publisher American Association for the Advancement of Science (AAAS)ca
• dc.relation.ispartof Science. 2012;338(6103):60-5
• dc.relation.projectID info:eu-repo/grantAgreement/EC/FP7/295129ca
• dc.relation.projectID info:eu-repo/grantAgreement/EC/FP7/268689
• dc.relation.projectID info:eu-repo/grantAgreement/EC/FP7/243914
• dc.relation.projectID info:eu-repo/grantAgreement/EC/FP7/269921
• dc.relation.projectID info:eu-repo/grantAgreement/ES/2PN/CDS-2007-00012
• dc.relation.projectID info:eu-repo/grantAgreement/ES/3PN/SAF2010-16085
• dc.rights © American Association for the Advancement of Science (AAAS) http://dx.doi.org/10.1126/science.1227356ca
• dc.rights.accessRights info:eu-repo/semantics/openAccessca
• dc.title Theory and simulation in neuroscienceca
• dc.type info:eu-repo/semantics/articleca
• dc.type.version info:eu-repo/semantics/submittedVersionca