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El repositorio institucional recoge, difunde y preserva la producción intelectual en formato digital que resulta de la actividad académica e investigadora de la UPF, las revistas científicas y las publicaciones institucionales. Su finalidad es contribuir a aumentar el impacto de la investigación hecha en la UPF y preservar la memoria intelectual de la UPF.

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Clinical presentations and outcomes related to tuberculosis in children younger than 2 years of age in Catalonia

Soriano-Arandes, Antoni; López Segura, María Nuria; Caylà i Busqueras, Joan A. (Frontiers, 2019)

Introduction: Children younger than 2 years have an increased risk of complications associated with tuberculosis (TB) due to the immaturity of the innate and adaptive immune response. We aimed to identify TB clinical ...
A combined transcriptomic and genomic analysis identifies a gene signature associated with the response to anti-TNF therapy in rheumatoid arthritis

Aterido, Adrià; Cañete Crespillo, Juan de Dios; Tornero, Jesús; Blanco, Francisco; Fernández-Gutiérrez, Benjamín; Pérez-García, Carolina; Alperiz, Mercedes; Olivé, Alex; Corominas, Héctor; Martínez-Taboada, Víctor; González-Alvaro, Isidoro; Fernández-Nebro, Antonio; Erra, Alba; López Lasanta, María; López Corbeto, Mireia; Palau, Núria; Marsal, Sara; Julià, Antonio (Frontiers, 2019)

Background: Rheumatoid arthritis (RA) is the most frequent autoimmune disease involving the joints. Although anti-TNF therapies have proven effective in the management of RA, approximately one third of patients do not show ...
Identification of genetic modifiers of penetrance in human inherited disease

Puigdevall Costa, Pau, 1991- (Universitat Pompeu Fabra, 2019-01-17)

Understanding the molecular basis of human inherited disease is a challenging task due to the complexity of mapping the genotype to the phenotype. The study of diseases running in families has shown that the inheritance ...
Non-vertical genomics in fungal evolution

Naranjo Ortiz, Miguel Ángel, 1989- (Universitat Pompeu Fabra, 2019-01-18)

Non-vertical genomic events, which include horizontal gene transfer (HGT) and hybridization, are widely studied evolutionary processes in certain groups. HGT is particularly well known for prokaryotic organisms, while ...
Computationl and modeling approaches to multi-scale anatomical description of neuronal circuitry

Manubens-Gil, Linus, 1989- (Universitat Pompeu Fabra, 2018-01-18)

During the last century the nervous system has been mainly studied from a reductionistic approach, based on the hypothesis that understanding in depth single neurons or limited neuronal populations would lead to general ...