Directed information exchange between cortical layers in macaque V1 and V4 and its modulation by selective attention

Mostra el registre complet Registre parcial de l'ítem

• dc.contributor.author Ferro, Demetrio
• dc.contributor.author van Kempen, Jochem
• dc.contributor.author Boyd, Michael
• dc.contributor.author Panzeri, Stefano
• dc.contributor.author Thiele, Alexander
• dc.date.accessioned 2021-04-08T08:21:12Z
• dc.date.available 2021-04-08T08:21:12Z
• dc.date.issued 2021
• dc.description.abstract Achieving behavioral goals requires integration of sensory and cognitive information across cortical laminae and cortical regions. How this computation is performed remains unknown. Using local field potential recordings and spectrally resolved conditional Granger causality (cGC) analysis, we mapped visual information flow, and its attentional modulation, between cortical layers within and between macaque brain areas V1 and V4. Stimulus-induced interlaminar information flow within V1 dominated upwardly, channeling information toward supragranular corticocortical output layers. Within V4, information flow dominated from granular to supragranular layers, but interactions between supragranular and infragranular layers dominated downwardly. Low-frequency across-area communication was stronger from V4 to V1, with little layer specificity. Gamma-band communication was stronger in the feedforward V1-to-V4 direction. Attention to the receptive field of V1 decreased communication between all V1 layers, except for granular-to-supragranular layer interactions. Communication within V4, and from V1 to V4, increased with attention across all frequencies. While communication from V4 to V1 was stronger in lower-frequency bands (4 to 25 Hz), attention modulated cGCs from V4 to V1 across all investigated frequencies. Our data show that top-down cognitive processes result in reduced communication within cortical areas, increased feedforward communication across all frequency bands, and increased gamma-band feedback communication.
• dc.description.sponsorship This research was funded by Wellcome Trust Grant 093104 (J.v.K., M.B., A.T.), Medical Research Council Grant MR/P013031/1 (J.v.K. and A.T.), NIH Brain Initiative Grants R01 NS108410 and U19 NS107464U19 (S.P.), and Simons Foundation Autism Research Initiative Explorer Grant 602849 (S.P.).
• dc.format.mimetype application/pdf
• dc.identifier.citation Ferro D, van Kempen J, Boyd M, Panzeri S, Thiele A. Directed information exchange between cortical layers in macaque V1 and V4 and its modulation by selective attention. Proc Natl Acad Sci. 2021;118(12):e2022097118. DOI: 10.1073/pnas.2022097118
• dc.identifier.doi http://dx.doi.org/10.1073/pnas.2022097118
• dc.identifier.issn 0027-8424
• dc.identifier.uri http://hdl.handle.net/10230/47045
• dc.language.iso eng
• dc.publisher National Academy of Sciences
• dc.relation.ispartof Proceedings of the Nationall Academy of Science of the United States of America. 2021;118(12):e2022097118
• dc.rights This open access article is distributed under Creative Commons Attribution License 4.0 (CC BY) https://creativecommons.org/licenses/by/4.0/
• dc.rights.accessRights info:eu-repo/semantics/openAccess
• dc.rights.uri https://creativecommons.org/licenses/by/4.0/
• dc.subject.keyword Attention
• dc.subject.keyword Feedforward processing
• dc.subject.keyword Feedback processing
• dc.subject.keyword Laminar interaction
• dc.title Directed information exchange between cortical layers in macaque V1 and V4 and its modulation by selective attention
• dc.type info:eu-repo/semantics/article
• dc.type.version info:eu-repo/semantics/publishedVersion