Quality of life in older patients after a heart failure hospitalization: results from the SENECOR Study

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• dc.contributor.author Luiso, Daniele
• dc.contributor.author Herrero-Torrus, Marta
• dc.contributor.author Badosa Marcé, Neus
• dc.contributor.author Roqueta, Cristina
• dc.contributor.author Ruiz-Bustillo, Sonia
• dc.contributor.author Belarte Tornero, Laia Carla
• dc.contributor.author Valdivielso Moré, Sandra
• dc.contributor.author Morales Murillo, Ronald Octavio
• dc.contributor.author Vázquez Ibar, Olga
• dc.contributor.author Farré López, Núria
• dc.date.accessioned 2022-11-17T07:53:02Z
• dc.date.available 2022-11-17T07:53:02Z
• dc.date.issued 2022
• dc.description.abstract Background: information about health-related quality of life (HRQoL) in heart failure (HF) in older adults is scarce. Methods: We aimed to describe the HRQoL of the SENECOR study cohort, a single-center, randomized trial comparing the effects of multidisciplinary intervention by a geriatrician and a cardiologist (intervention group) to that of a cardiologist alone (control group) in older patients with a recent HF hospitalization. Results: HRQoL was assessed by the short version of the disease-specific Kansas Cardiomyopathy Questionnaire (KCCQ-12) in 141 patients at baseline and was impaired (KCCQ-12 < 75) in almost half of the cohort. Women comprised 50% of the population, the mean age was 82.2 years, and two-thirds of patients had preserved ejection fraction. Comorbidities were highly prevalent. Patients with impaired HRQoL had a worse NYHA functional class, a lower NT-proBNP, a lower Barthel index, and a higher Clinical Frailty Scale. One-year all-cause mortality was 22.7%, significantly lower in the group with good-to-excellent HRQoL (14.5% vs. 30.6%; hazard ratio 0.28; 95% confidence interval 0.10-0.78; p = 0.014). In the group with better HRQoL, all-cause hospitalization was lower, and there was a trend towards lower HF hospitalization. Conclusions: the KCCQ-12 questionnaire can provide inexpensive prognostic information even in older patients with HF. (Funded by grant Primitivo de la Vega, Fundación MAPFRE. ClinicalTrials number, NCT03555318).
• dc.format.mimetype application/pdf
• dc.identifier.citation Luiso D, Herrero-Torrus M, Badosa N, Roqueta C, Ruiz-Bustillo S, Belarte-Tornero LC, et al. Quality of life in older patients after a heart failure hospitalization: results from the SENECOR Study. J Clin Med. 2022 May 27; 11(11):3035. DOI: 10.3390/jcm11113035
• dc.identifier.doi http://dx.doi.org/10.3390/jcm11113035
• dc.identifier.issn 2077-0383
• dc.identifier.uri http://hdl.handle.net/10230/54906
• dc.language.iso eng
• dc.publisher MDPI
• dc.rights Copyright © 2022 by Luiso D, Herrero-Torrus M, Badosa N, Roqueta C, Ruiz-Bustillo S, Belarte-Tornero LC, et al. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
• dc.rights.accessRights info:eu-repo/semantics/openAccess
• dc.rights.uri http://creativecommons.org/licenses/by/4.0/
• dc.subject.keyword Heart failure
• dc.subject.keyword Older patients
• dc.subject.keyword Prognosis
• dc.subject.keyword Quality of life
• dc.title Quality of life in older patients after a heart failure hospitalization: results from the SENECOR Study
• dc.type info:eu-repo/semantics/article
• dc.type.version info:eu-repo/semantics/publishedVersion