Quality of life in older patients after a heart failure hospitalization: results from the SENECOR Study

Luiso, Daniele; Herrero-Torrus, Marta; Badosa Marcé, Neus; Roqueta, Cristina; Ruiz-Bustillo, Sonia; Belarte Tornero, Laia Carla; Valdivielso Moré, Sandra; Morales Murillo, Ronald Octavio; Vázquez Ibar, Olga; Farré López, Núria

doi:http://dx.doi.org/10.3390/jcm11113035

Quality of life in older patients after a heart failure hospitalization: results from the SENECOR Study

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Luiso D, Herrero-Torrus M, Badosa N, Roqueta C, Ruiz-Bustillo S, Belarte-Tornero LC, et al. Quality of life in older patients after a heart failure hospitalization: results from the SENECOR Study. J Clin Med. 2022 May 27; 11(11):3035. DOI: 10.3390/jcm11113035

Abstract

Background: information about health-related quality of life (HRQoL) in heart failure (HF) in older adults is scarce. Methods: We aimed to describe the HRQoL of the SENECOR study cohort, a single-center, randomized trial comparing the effects of multidisciplinary intervention by a geriatrician and a cardiologist (intervention group) to that of a cardiologist alone (control group) in older patients with a recent HF hospitalization. Results: HRQoL was assessed by the short version of the disease-specific Kansas Cardiomyopathy Questionnaire (KCCQ-12) in 141 patients at baseline and was impaired (KCCQ-12 < 75) in almost half of the cohort. Women comprised 50% of the population, the mean age was 82.2 years, and two-thirds of patients had preserved ejection fraction. Comorbidities were highly prevalent. Patients with impaired HRQoL had a worse NYHA functional class, a lower NT-proBNP, a lower Barthel index, and a higher Clinical Frailty Scale. One-year all-cause mortality was 22.7%, significantly lower in the group with good-to-excellent HRQoL (14.5% vs. 30.6%; hazard ratio 0.28; 95% confidence interval 0.10-0.78; p = 0.014). In the group with better HRQoL, all-cause hospitalization was lower, and there was a trend towards lower HF hospitalization. Conclusions: the KCCQ-12 questionnaire can provide inexpensive prognostic information even in older patients with HF. (Funded by grant Primitivo de la Vega, Fundación MAPFRE. ClinicalTrials number, NCT03555318).