The eTRANSAFE project on translational safety assessment through integrative knowledge management: achievements and perspectives
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- dc.contributor.author Pognan, François
- dc.contributor.author Centeno, Emilio
- dc.contributor.author Furlong, Laura I., 1971-
- dc.contributor.author Guney, Emre
- dc.contributor.author Mayer, Miguel Ángel, 1960-
- dc.contributor.author Pastor Maeso, Manuel
- dc.contributor.author Piñero González, Janet, 1977-
- dc.contributor.author Ramírez Anguita, Juan Manuel
- dc.contributor.author Ronzano, Francesco
- dc.contributor.author Saüch Pitarch, Josep
- dc.contributor.author Sanz, Ferran
- dc.date.accessioned 2021-04-12T07:07:24Z
- dc.date.available 2021-04-12T07:07:24Z
- dc.date.issued 2021
- dc.description.abstract eTRANSAFE is a research project funded within the Innovative Medicines Initiative (IMI), which aims at developing integrated databases and computational tools (the eTRANSAFE ToxHub) that support the translational safety assessment of new drugs by using legacy data provided by the pharmaceutical companies that participate in the project. The project objectives include the development of databases containing preclinical and clinical data, computational systems for translational analysis including tools for data query, analysis and visualization, as well as computational models to explain and predict drug safety events.
- dc.description.sponsorship This research received funding from the Innovative Medicines Initiative 2 Joint Undertaking under grant agreements eTRANSAFE (777365). This Joint Undertaking receives support from the European Union’s Horizon 2020 research and innovation programme and EFPIA companies in kind contribution.
- dc.format.mimetype application/pdf
- dc.identifier.citation Pognan F, Steger-Hartmann T, Díaz C, Blomberg N, Bringezu F, Briggs K et al. The eTRANSAFE project on translational safety assessment through integrative knowledge management: achievements and perspectives. Pharmaceuticals (Basel). 2021; 14(3):237. DOI: 10.3390/ph14030237
- dc.identifier.doi http://dx.doi.org/10.3390/ph14030237
- dc.identifier.issn 1424-8247
- dc.identifier.uri http://hdl.handle.net/10230/47087
- dc.language.iso eng
- dc.publisher MDPI
- dc.relation.ispartof Pharmaceuticals (Basel). 2021; 14(3):237
- dc.relation.projectID info:eu-repo/grantAgreement/EC/H2020/777365
- dc.rights © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
- dc.rights.accessRights info:eu-repo/semantics/openAccess
- dc.rights.uri http://creativecommons.org/licenses/by/4.0/
- dc.subject.keyword Data mining
- dc.subject.keyword Data sharing
- dc.subject.keyword Drug safety
- dc.subject.keyword Integrative knowledge management
- dc.subject.keyword Predictive modelling
- dc.subject.keyword Read across
- dc.subject.keyword Toxicology
- dc.subject.keyword Translational safety assessment
- dc.title The eTRANSAFE project on translational safety assessment through integrative knowledge management: achievements and perspectives
- dc.type info:eu-repo/semantics/article
- dc.type.version info:eu-repo/semantics/publishedVersion