The eTRANSAFE project on translational safety assessment through integrative knowledge management: achievements and perspectives

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dc.contributor.authorPognan, François
dc.contributor.authorCenteno, Emilio
dc.contributor.authorFurlong, Laura I., 1971-
dc.contributor.authorGuney, Emre
dc.contributor.authorMayer, Miguel Ángel, 1960-
dc.contributor.authorPastor Maeso, Manuel
dc.contributor.authorPiñero González, Janet, 1977-
dc.contributor.authorRamírez Anguita, Juan Manuel
dc.contributor.authorRonzano, Francesco
dc.contributor.authorSaüch Pitarch, Josep
dc.contributor.authorSanz, Ferran
dc.date.accessioned2021-04-12T07:07:24Z
dc.date.available2021-04-12T07:07:24Z
dc.date.issued2021
dc.description.abstracteTRANSAFE is a research project funded within the Innovative Medicines Initiative (IMI), which aims at developing integrated databases and computational tools (the eTRANSAFE ToxHub) that support the translational safety assessment of new drugs by using legacy data provided by the pharmaceutical companies that participate in the project. The project objectives include the development of databases containing preclinical and clinical data, computational systems for translational analysis including tools for data query, analysis and visualization, as well as computational models to explain and predict drug safety events.
dc.description.sponsorshipThis research received funding from the Innovative Medicines Initiative 2 Joint Undertaking under grant agreements eTRANSAFE (777365). This Joint Undertaking receives support from the European Union’s Horizon 2020 research and innovation programme and EFPIA companies in kind contribution.
dc.format.mimetypeapplication/pdf
dc.identifier.citationPognan F, Steger-Hartmann T, Díaz C, Blomberg N, Bringezu F, Briggs K et al. The eTRANSAFE project on translational safety assessment through integrative knowledge management: achievements and perspectives. Pharmaceuticals (Basel). 2021; 14(3):237. DOI: 10.3390/ph14030237
dc.identifier.doihttp://dx.doi.org/10.3390/ph14030237
dc.identifier.issn1424-8247
dc.identifier.urihttp://hdl.handle.net/10230/47087
dc.language.isoeng
dc.publisherMDPI
dc.relation.ispartofPharmaceuticals (Basel). 2021; 14(3):237
dc.relation.projectIDinfo:eu-repo/grantAgreement/EC/H2020/777365
dc.rights© 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subject.keywordData mining
dc.subject.keywordData sharing
dc.subject.keywordDrug safety
dc.subject.keywordIntegrative knowledge management
dc.subject.keywordPredictive modelling
dc.subject.keywordRead across
dc.subject.keywordToxicology
dc.subject.keywordTranslational safety assessment
dc.titleThe eTRANSAFE project on translational safety assessment through integrative knowledge management: achievements and perspectives
dc.typeinfo:eu-repo/semantics/article
dc.type.versioninfo:eu-repo/semantics/publishedVersion

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