The eTRANSAFE project on translational safety assessment through integrative knowledge management: achievements and perspectives
The eTRANSAFE project on translational safety assessment through integrative knowledge management: achievements and perspectives
Citació
- Pognan F, Steger-Hartmann T, Díaz C, Blomberg N, Bringezu F, Briggs K et al. The eTRANSAFE project on translational safety assessment through integrative knowledge management: achievements and perspectives. Pharmaceuticals (Basel). 2021; 14(3):237. DOI: 10.3390/ph14030237
Enllaç permanent
Descripció
Resum
eTRANSAFE is a research project funded within the Innovative Medicines Initiative (IMI), which aims at developing integrated databases and computational tools (the eTRANSAFE ToxHub) that support the translational safety assessment of new drugs by using legacy data provided by the pharmaceutical companies that participate in the project. The project objectives include the development of databases containing preclinical and clinical data, computational systems for translational analysis including tools for data query, analysis and visualization, as well as computational models to explain and predict drug safety events.