Spontaneous brain activity predicts learning ability of foreign sounds

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• dc.contributor.author Ventura Campos, Noeliaca
• dc.contributor.author Sanjuán, Anaca
• dc.contributor.author González, Julioca
• dc.contributor.author Palomar García, María Ángelesca
• dc.contributor.author Rodríguez Pujadas, Ainaca
• dc.contributor.author Sebastián Gallés, Núriaca
• dc.contributor.author Deco, Gustavoca
• dc.contributor.author Ávila, Césarca
• dc.date.accessioned 2015-01-27T08:31:57Z
• dc.date.available 2015-01-27T08:31:57Z
• dc.date.issued 2013ca
• dc.description.abstract Can learning capacity of the human brain be predicted from initial spontaneous functional connectivity (FC) between brain areas involved in a task? We combined task-related functional magnetic resonance imaging (fMRI) and resting-state fMRI (rs-fMRI) before and after training with a Hindi dental–retroflex nonnative contrast. Previous fMRI results were replicated, demonstrating that this learning recruited the left insula/frontal operculum and the left superior parietal lobe, among other areas of the brain. Crucially, resting-state FC (rs-FC) between these two areas at pretraining predicted individual differences in learning outcomes after distributed (Experiment 1) and intensive training (Experiment 2). Furthermore, this rs-FC was reduced at posttraining, a change that may also account for learning. Finally, resting-state network analyses showed that the mechanism underlying this reduction of rs-FC was mainly a transfer in intrinsic activity of the left frontal operculum/anterior insula from the left frontoparietal network to the salience network. Thus, rs-FC may contribute to predict learning ability and to understand how learning modifies the functioning of the brain. The discovery of this correspondence between initial spontaneous brain activity in task-related areas and posttraining performance opens new avenues to find predictors of learning capacities in the brain using task-related fMRI and rs-fMRI combined.en
• dc.description.sponsorship This work was supported in part by Spanish Ministerio de Ciencia e Innovacio/ńn Grants PSI2010-20168, PSI2012-/n34071, and CONSOLIDER-INGENIO 2010 Programme CDS-2007-00012, Generalitat Valenciana Grant APOSTD//n2012068, and Universitat Jaume I Grant P1-1B2012-38. G.D. was supported by the ERC Advanced Grant/nDYSTRUCTURE (no. 295129). by the Spanish Research Project SAF2010-16085, and by the CONSOLIDER-INGENIO/n2010 Program CSD2007-00012
• dc.format.extent 11 p.
• dc.format.mimetype application/pdfca
• dc.identifier.citation Ventura N, Sanjuán A, González J, Palomar MA, Rodríguez A, Sebastián N, Deco G, Ávila C. Spontaneous brain activity predicts learning ability of foreign sounds. J Neurosci. 2013 May;33(22):9295-305. DOI 10.1523/JNEUROSCI.4655-12.2013.ca
• dc.identifier.doi http://dx.doi.org/10.1523/JNEUROSCI.4655-12.2013
• dc.identifier.issn 0270-6474ca
• dc.identifier.uri http://hdl.handle.net/10230/23075
• dc.language.iso engca
• dc.publisher Society for Neuroscienceca
• dc.relation.ispartof The Journal of Neuroscience. 2013 May;33(22):9295-305
• dc.relation.projectID info:eu-repo/grantAgreement/EC/FP7/295129ca
• dc.relation.projectID info:eu-repo/grantAgreement/ES/3PN/PSI2012-34071
• dc.relation.projectID info:eu-repo/grantAgreement/ES/3PN/SAF2010-16085
• dc.relation.projectID info:eu-repo/grantAgreement/ES/3PN/PSI2010-20168
• dc.rights The work is published under a Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/ca
• dc.rights.accessRights info:eu-repo/semantics/openAccessca
• dc.rights.uri http://creativecommons.org/licenses/by-nc-sa/3.0/
• dc.title Spontaneous brain activity predicts learning ability of foreign soundsca
• dc.type info:eu-repo/semantics/articleca
• dc.type.version info:eu-repo/semantics/publishedVersionca