Numerical analysis of thermal impact of intramyocardial capillary blood flow during radiofrequency cardiac ablation
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- dc.contributor.author Pérez, Juan J.ca
- dc.contributor.author González-Suárez, Anaca
- dc.contributor.author Berjano, Enrique J.ca
- dc.date.accessioned 2017-11-28T16:46:36Z
- dc.date.issued 2018
- dc.description.abstract The thermal effect of the intramyocardial blood perfusion on the size of lesions created by radiofrequency cardiac ablation (RFCA) has not been adequately studied to date. Our objective was to assess the impact of including this phenomenon in RFCA computer modelling in terms of the thermal lesion depth created. Methods: A computer model was built and computer simulations were conducted to assess the effect of including the blood perfusion term in the bioheat equation. This term mimics the intramyocardial blood flow (i.e., blood perfusion) in the cardiac wall at the site at which the RFCA is being conducted and hence represents a heat removing mechanism. When considered, blood perfusion rates ranged from 609 to 1719 ml/min/kg. Two electrode design and modes were considered: a non-irrigated elec- trode with constant temperature mode and an irrigated electrode with constant power mode. Results: All the depths computed without including the blood perfusion term were larger than those that did include it, regardless of perfusion rate. The differences in lesion depth between ignoring and including blood perfusion increased over time; for a 60 s RFCA they were 0.45 and 1 mm for minimum and maximum perfusion rate, respectively. The differences were more or less independent of blood flow in the cardiac chamber, electrode type and ablation mode. Conclusions: The findings suggest that the heat-sink effect of blood perfusion should be taken into account in the case of ablations ( > 1 minute) such as those conducted in RFCA of the ventricular wall.en
- dc.description.sponsorship This work was supported by the Ministerio de Economía y Competitividad under “Plan Estatal de Investigación, Desarrollo e Innovación Orientada a los Retos de la Sociedad” Grant “TEC2014-52383-C3 [TEC2014-52383-C3-1-R]”. A. González-Suáarez had a Postdoctoral Grant [APOSTD/2016/045] from the Generalitat Valenciana (Spain) and currently has a Postdoctoral Grant “Juan de la Cierva-formación” [FJCI-2015-27202] supported by the Spanish Ministerio de Economía, Industria y Competitividad.en
- dc.format.mimetype application/pdfca
- dc.identifier.citation Pérez JJ, González-Suárez A, Berjano E. Numerical analysis of thermal impact of intramyocardial capillary blood flow during radiofrequency cardiac ablation. Int J Hyperthermia. 2018;34(3):243-9. DOI: 10.1080/02656736.2017.1336258
- dc.identifier.doi http://dx.doi.org/10.1080/02656736.2017.1336258
- dc.identifier.issn 0265-6736
- dc.identifier.uri http://hdl.handle.net/10230/33367
- dc.language.iso eng
- dc.publisher Taylor & Francis (Routledge)ca
- dc.relation.ispartof International Journal of Hyperthermia. 2018;34(3):243-9
- dc.rights © Taylor & Francis. This is an electronic version of an article published in Pérez JJ, González-Suárez A, Berjano E. Numerical analysis of thermal impact of intramyocardial capillary blood flow during radiofrequency cardiac ablation. Int J Hyperthermia. 2018;34(3):243-9. International Journal of Hyperthermia is available online at: www.tandfonline.com [with the open URL of your article].
- dc.rights.accessRights info:eu-repo/semantics/openAccess
- dc.subject.keyword Blood perfusionen
- dc.subject.keyword Cardiac ablationen
- dc.subject.keyword Computer modelen
- dc.subject.keyword Intramyocardial blood flowen
- dc.subject.keyword Radiofrequency ablationen
- dc.title Numerical analysis of thermal impact of intramyocardial capillary blood flow during radiofrequency cardiac ablationca
- dc.type info:eu-repo/semantics/article
- dc.type.version info:eu-repo/semantics/acceptedVersion