Fully automatic detection and segmentation of abdominal aortic thrombus in post-operative CTA images using Deep Convolutional Neural Networks

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• dc.contributor.author López-Linares, Karen
• dc.contributor.author Aranjuelo, Nerea
• dc.contributor.author Kabongo, Luis
• dc.contributor.author Maclair, Gregory
• dc.contributor.author Lete, Nerea
• dc.contributor.author Ceresa, Mario
• dc.contributor.author García-Familiar, Ainhoa
• dc.contributor.author Macía, Iván
• dc.contributor.author González Ballester, Miguel Ángel, 1973-
• dc.date.accessioned 2021-06-17T07:11:10Z
• dc.date.available 2021-06-17T07:11:10Z
• dc.date.issued 2018
• dc.description.abstract Computerized Tomography Angiography (CTA) based follow-up of Abdominal Aortic Aneurysms (AAA) treated with Endovascular Aneurysm Repair (EVAR) is essential to evaluate the progress of the patient and detect complications. In this context, accurate quantification of post-operative thrombus volume is required. However, a proper evaluation is hindered by the lack of automatic, robust and reproducible thrombus segmentation algorithms. We propose a new fully automatic approach based on Deep Convolutional Neural Networks (DCNN) for robust and reproducible thrombus region of interest detection and subsequent fine thrombus segmentation. The DetecNet detection network is adapted to perform region of interest extraction from a complete CTA and a new segmentation network architecture, based on Fully Convolutional Networks and a Holistically-Nested Edge Detection Network, is presented. These networks are trained, validated and tested in 13 post-operative CTA volumes of different patients using a 4-fold cross-validation approach to provide more robustness to the results. Our pipeline achieves a Dice score of more than 82% for post-operative thrombus segmentation and provides a mean relative volume difference between ground truth and automatic segmentation that lays within the experienced human observer variance without the need of human intervention in most common cases.
• dc.description.sponsorship This work has been supported by the DEFENSE (TIN2013-47913-C3) research project, funded by the Ministry of Economy and Competitiveness-Government of Spain.
• dc.format.mimetype application/pdf
• dc.identifier.citation López-Linares K, Aranjuelo N, Kabongo L, Maclair G, Lete N, Ceresa M, García-Familiar A, Macía I, González Ballester MA. Fully automatic detection and segmentation of abdominal aortic thrombus in post-operative CTA images using Deep Convolutional Neural Networks. Med Image Anal. 2018;46:202-14. DOI: 10.1016/j.media.2018.03.010
• dc.identifier.doi http://dx.doi.org/10.1016/j.media.2018.03.010
• dc.identifier.issn 1361-8415
• dc.identifier.uri http://hdl.handle.net/10230/47919
• dc.language.iso eng
• dc.publisher Elsevier
• dc.relation.ispartof Medical Image Analysis. 2018;46:202-14
• dc.relation.projectID info:eu-repo/grantAgreement/ES/1PE/TIN2013-47913-C3
• dc.rights © Elsevier http://dx.doi.org/10.1016/j.media.2018.03.010
• dc.rights.accessRights info:eu-repo/semantics/openAccess
• dc.subject.keyword AAA
• dc.subject.keyword EVAR
• dc.subject.keyword Segmentation
• dc.subject.keyword DCNN
• dc.subject.keyword Deep learning
• dc.subject.keyword Thrombus
• dc.subject.keyword Post-operative
• dc.subject.keyword Detection
• dc.title Fully automatic detection and segmentation of abdominal aortic thrombus in post-operative CTA images using Deep Convolutional Neural Networks
• dc.type info:eu-repo/semantics/article
• dc.type.version info:eu-repo/semantics/acceptedVersion