The Global dynamical complexity of the human brain network

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• dc.contributor.author Arsiwalla, Xerxes D.ca
• dc.contributor.author Verschure, Paul F. M. J.ca
• dc.date.accessioned 2017-10-04T13:31:37Z
• dc.date.available 2017-10-04T13:31:37Z
• dc.date.issued 2016
• dc.description.abstract How much information do large brain networks integrate as a whole over the sum of their parts? Can the dynamical complexity of such networks be globally quantified in an information-theoretic way and be meaningfully coupled to brain function? Recently, measures of dynamical complexity such as integrated information have been proposed. However, problems related to the normalization and Bell number of partitions associated to these measures make these approaches computationally infeasible for large-scale brain networks. Our goal in this work is to address this problem. Our formulation of network integrated information is based on the Kullback-Leibler divergence between the multivariate distribution on the set of network states versus the corresponding factorized distribution over its parts. We find that implementing the maximum information partition optimizes computations. These methods are well-suited for large networks with linear stochastic dynamics. We compute the integrated information for both, the system’s attractor states, as well as non-stationary dynamical states of the network. We then apply this formalism to brain networks to compute the integrated information for the human brain’s connectome. Compared to a randomly re-wired network, we find that the specific topology of the brain generates greater information complexity.en
• dc.description.sponsorship This work has been supported by the European Research Council’s CDAC project: “The Role of Consciousness in Adaptive Behavior: A Combined Empirical, Computational and Robot based Approach” (ERC-2013- ADG 341196).en
• dc.format.mimetype application/pdf
• dc.identifier.citation Arsiwalla XD, Verschure PFMJ. The Global dynamical complexity of the human brain network. Applied Network Science. 2016;1:16 p. DOI: 10.1007/s41109-016-0018-8
• dc.identifier.doi http://dx.doi.org/10.1007/s41109-016-0018-8
• dc.identifier.issn 2364-8228
• dc.identifier.uri http://hdl.handle.net/10230/32850
• dc.language.iso eng
• dc.publisher SpringerOpenca
• dc.relation.ispartof Applied Network Science. 2016;1:16 p.
• dc.relation.projectID info:eu-repo/grantAgreement/EC/FP7/341196
• dc.rights This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
• dc.rights.accessRights info:eu-repo/semantics/openAccess
• dc.rights.uri http://creativecommons.org/licenses/by/4.0/
• dc.subject.keyword Brain networksen
• dc.subject.keyword Neural dynamicsen
• dc.subject.keyword Complexity measuresen
• dc.title The Global dynamical complexity of the human brain networkca
• dc.type info:eu-repo/semantics/article
• dc.type.version info:eu-repo/semantics/publishedVersion