Protein transport by vesicles and tunnels

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  • dc.contributor.author Raote, Ishier
  • dc.contributor.author Malhotra, Vivek
  • dc.date.accessioned 2019-09-17T16:02:03Z
  • dc.date.available 2019-09-17T16:02:03Z
  • dc.date.issued 2019
  • dc.description.abstract Palade's corpus placed small vesicles as the sole means to transport proteins across stable distinct compartments of the secretory pathway. We suggest that cargo, spatial organization of secretory compartments, and the timing of fission of cargo-filled containers dictate the design of transport intermediates that can be vesicles and transient direct tunnels.
  • dc.description.sponsorship We acknowledge support from the Spanish Ministry of Economy and Competitiveness through the Program “Centro de Excelencia Severo Ochoa 2013-2017” (SEV-2012-0208), support from the CERCA Program/Generalitat de Catalunya and fellowship IJCI-2017-34751 (to I. Raote). V. Malhotra is an Institució Catalana de Recerca i Estudis Avançats professor at the Centre for Genomic Regulation and the work in his laboratory is funded by grants from MINECO’s Plan Nacional (BFU2013-44188-P) and Consolider (CSD2009-00016). The project has received research funding from the European Union. This paper reflects only the authors’ views. The European Union is not liable for any use that may be made of the information contained therein.
  • dc.format.mimetype application/pdf
  • dc.identifier.citation Raote I, Malhotra V. Protein transport by vesicles and tunnels. J Cell Biol. 2019 Mar 4;218(3):737-9. DOI: 10.1083/jcb.201811073
  • dc.identifier.doi http://dx.doi.org/10.1083/jcb.201811073
  • dc.identifier.issn 0021-9525
  • dc.identifier.uri http://hdl.handle.net/10230/42286
  • dc.language.iso eng
  • dc.publisher Rockefeller University Press
  • dc.relation.ispartof Journal of Cell Biology. 2019 Mar 4;218(3):737-9
  • dc.relation.projectID info:eu-repo/grantAgreement/ES/1PE/BFU2013-44188-P
  • dc.rights © 2019 Raote and Malhotra. This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/)
  • dc.rights.accessRights info:eu-repo/semantics/openAccess
  • dc.rights.uri https://creativecommons.org/licenses/by-nc-sa/4.0/
  • dc.title Protein transport by vesicles and tunnels
  • dc.type info:eu-repo/semantics/article
  • dc.type.version info:eu-repo/semantics/publishedVersion

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Articles (Center for Genomic Regulation (CRG))
Articles (Departament de Medicina i Ciències de la Vida)