Protein transport by vesicles and tunnels

Raote, Ishier; Malhotra, Vivek

doi:http://dx.doi.org/10.1083/jcb.201811073

Protein transport by vesicles and tunnels

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Raote I, Malhotra V. Protein transport by vesicles and tunnels. J Cell Biol. 2019 Mar 4;218(3):737-9. DOI: 10.1083/jcb.201811073

Abstract

Palade's corpus placed small vesicles as the sole means to transport proteins across stable distinct compartments of the secretory pathway. We suggest that cargo, spatial organization of secretory compartments, and the timing of fission of cargo-filled containers dictate the design of transport intermediates that can be vesicles and transient direct tunnels.