Clinical relevance of interictal dysphoric disorder and its impact on quality of life in drug-resistant epilepsy
Mostra el registre complet Registre parcial de l'ítem
- dc.contributor.author Monteagudo-Gimeno, Eila
- dc.contributor.author Sánchez-González, Roberto
- dc.contributor.author Raduà Castaño, Joaquim
- dc.contributor.author Fortea-González, Lydia
- dc.contributor.author Boget Llucià, Teresa
- dc.contributor.author Carreño Martínez, Mar
- dc.contributor.author Donaire Pedraza, Antonio J.
- dc.contributor.author Bargalló Alabart, Núria
- dc.contributor.author Setoain Perego, Xavier
- dc.contributor.author Rumià Arboix, Jordi
- dc.contributor.author Bulbena Vilarrasa, Antonio
- dc.contributor.author Pintor-Pérez, Luis
- dc.date.accessioned 2024-03-01T07:31:04Z
- dc.date.available 2024-03-01T07:31:04Z
- dc.date.issued 2023
- dc.description.abstract Objective: This study aims to assess the prevalence of Interictal Dysphoric Disorder (IDD) in drug-resistant epilepsy (DRE) and to describe its clinical and psychopathological profile, including personality, as well as its impact on quality of life (QOL). Method: A retrospective cross-sectional study from an Epilepsy Unit from January 2007 to December 2017. All patients were diagnosed with DRE. Patients underwent a battery of tests (HADS, SCL-90R, PDQ-4+, QOLIE-31) and a psychiatrist assessed the presence of Axis-I disorders and IDD. Statistical procedures were carried out using R-4.0.1 software. Results: A total of 282 patients were included. A statistically significant association was found between IDD and mood and anxiety disorders (p < 0.001 and p < 0.05 respectively), and between IDD and higher scores in all HADS and SCL-90-R items compared to subjects without IDD (p < 0.001). A statistically significant association was also found between IDD and obsessive-compulsive, borderline and depressive personality disorder (p < 0.05). Scores in all QOLIE-31 items except for 'medication effects' were significantly lower in subjects with IDD compared with subjects without IDD (p < 0.001). Conclusions: In DRE, IDD subjects show differences in the psychopathological profile and QOL scores compared to subjects without a diagnosis of IDD. An early diagnosis of IDD could facilitate prompt interventions which might positively impact QOL.
- dc.format.mimetype application/pdf
- dc.identifier.citation Monteagudo-Gimeno E, Sánchez-González R, Raduà-Castaño J, Fortea-González L, Boget-Llucià T, Carreño-Martínez M, Donaire-Pedraza A, Bargalló-Alabart N, Setoain-Perego X, Rumià-Arboix J, Bulbena-Vilarrasa A, Pintor-Pérez L. Clinical relevance of interictal dysphoric disorder and its impact on quality of life in drug-resistant epilepsy. Epilepsy Behav. 2023 Jul;144:109253. DOI: 10.1016/j.yebeh.2023.109253
- dc.identifier.doi http://dx.doi.org/10.1016/j.yebeh.2023.109253
- dc.identifier.issn 1525-5050
- dc.identifier.uri http://hdl.handle.net/10230/59300
- dc.language.iso eng
- dc.publisher Elsevier
- dc.relation.ispartof Epilepsy Behav. 2023 Jul;144:109253
- dc.rights © 2023 The Author(s). Published by Elsevier Inc. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
- dc.rights.accessRights info:eu-repo/semantics/openAccess
- dc.rights.uri http://creativecommons.org/licenses/by/4.0/
- dc.subject.keyword Drug-Resistant Epilepsy
- dc.subject.keyword Interictal Dysphoric Disorder
- dc.subject.keyword Psychopathology
- dc.title Clinical relevance of interictal dysphoric disorder and its impact on quality of life in drug-resistant epilepsy
- dc.type info:eu-repo/semantics/article
- dc.type.version info:eu-repo/semantics/publishedVersion