Atrial functional and geometrical remodeling in highly trained male athletes: for better or worse?

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• dc.contributor.author Gabrielli, Luigi
• dc.contributor.author Bijnens, Bart
• dc.contributor.author Butakoff, Constantine
• dc.contributor.author Duchateau, Nicolas
• dc.contributor.author Montserrat, Silvia
• dc.contributor.author Merino, Beatriz
• dc.contributor.author Gutierrez, Josep Antoni
• dc.contributor.author Paré, Carles
• dc.contributor.author Mont, Lluís
• dc.contributor.author Brugada, Josep
• dc.contributor.author Sitges, Marta
• dc.date.accessioned 2020-02-06T14:44:14Z
• dc.date.available 2020-02-06T14:44:14Z
• dc.date.issued 2014
• dc.description.abstract Purpose Highly trained athletes have an increased risk of atrial arrhythmias. Atrial geometrical and functional remodeling may be the underlying substrate. We analyze and relate atrial size, deformation and performance in professional handball players compared with non-sportive subjects. Methods 24 Professional handball players and 20 non-sportive males were compared. All subjects underwent an echocardiographic study with evaluation of left (LA), right atrial (RA) dimensions and deformation by strain (Sa) and strain rate (SRa). Atrial performance was assessed from the atrial stroke volume (SV). With computational geometrical models, we studied the relation between atrial volumes, strains and SV and compared atrial working conditions. We estimated the functional reserve and a resulting average wall stress. Results LA and RA volumes were larger in athletes than in controls (35.2 ± 8.8 vs. 24.8 ± 4.3 ml/m2, p < 0.01 and 29.0 ± 8.4 vs. 19.0 ± 5.1 ml/m2, p < 0.01 respectively). LASa and RASa during active atrial contraction were decreased in athletes (−12.2 ± 2.0 vs. −14.5 ± 2.1 %, p < 0.01 and −12.1 ± 1.8 vs. −14.2 ± 1.5 %, p < 0.01 respectively). LASV was similar between groups (6.6 ± 1.4 vs. 7.3 ± 1.1 ml, p = 0.19) and RASV was lower in athletes (6.2 ± 1.3 vs. 7.2 ± 1.1 ml, p < 0.01). Computational models showed that this different operational mode potentially increases performance reserve, but at the cost of higher atrial wall stress. Conclusion A proportion of athletes with enlarged LA and RA showed different atrial contractile performance, likely resulting in atria working at higher wall stress.
• dc.description.sponsorship This study was partially supported by Grants from the “Generalitat de Catalunya (Consell Catala de l’Esport)”, from “Grupo Memora (SFB-Grupo Memora)”, Spanish Society of Cardiology (Spanish Heart Foundation), from the “Plan Nacional I + D + I”, Spanish Government (DEP2010-20565), and from the “Subprograma de Proyectos en Salud”, Instituto de Salud Carlos III, Spanish Government (FIS—PI11/01709).
• dc.format.mimetype application/pdf
• dc.identifier.citation Gabrielli L, Bijnens B, Butakoff C, Duchateau N, Montserrat S, Merino B, Gutierrez J, Paré C, Mont L, Brugada J, Sitges M. Atrial functional and geometrical remodeling in highly trained male athletes: for better or worse?. Eur J Appl Physiol. 2014;114(6):1143-52. DOI: 10.1007/s00421-014-2845-6
• dc.identifier.doi http://dx.doi.org/10.1007/s00421-014-2845-6
• dc.identifier.issn 1439-6319
• dc.identifier.uri http://hdl.handle.net/10230/43505
• dc.language.iso eng
• dc.publisher Springer
• dc.relation.ispartof European Journal of Applied Physiology. 2014;114(6):1143-52.
• dc.relation.projectID info:eu-repo/grantAgreement/ES/3PN/DEP2010-20565
• dc.rights © Springer The final publication is available at Springer via http://dx.doi.org/10.1007/s00421-014-2845-6.
• dc.rights.accessRights info:eu-repo/semantics/openAccess
• dc.subject.keyword Atrial strain
• dc.subject.keyword Atrial function
• dc.subject.keyword Echocardiography
• dc.subject.keyword Wall stress
• dc.subject.keyword Exercise
• dc.title Atrial functional and geometrical remodeling in highly trained male athletes: for better or worse?
• dc.type info:eu-repo/semantics/article
• dc.type.version info:eu-repo/semantics/acceptedVersion