A versatile multilevel converter platform for cancer treatment using irreversible electroporation

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• dc.contributor.author Sarnago, Héctorca
• dc.contributor.author Lucía, Óscarca
• dc.contributor.author Naval, Alejandroca
• dc.contributor.author Burdío, José M.ca
• dc.contributor.author Castellví Fernández, Quimca
• dc.contributor.author Ivorra Cano, Antoni, 1974-ca
• dc.date.accessioned 2016-04-21T12:17:39Z
• dc.date.available 2016-04-21T12:17:39Z
• dc.date.issued 2016ca
• dc.description.abstract Electroporation is an effective technique based on applying an electric field to cells, commonly used to increase the effectivity of drug and gene delivery. When the applied electric field is strong enough, it can be used for selective cell death with promising results in cancer treatment. This paper proposes the development of a modular multilevel topology in order to provide a high-performance tool for research in electroporation. The proposed converter based on a scalable multicell approach is detailed and analyzed in this paper, and an experimental prototype has been designed and built. The experimental results prove the feasibility of this proposal to enable advanced electroporation techniques.en
• dc.description.sponsorship This work was supported in part by Diputación General de Aragón-Fondo Social Europeo, in part by the University of Zaragoza/nunder Grant JIUZ-2014-TEC-08, and in part by the Spanish Ministerio de Economía y Competitividad under Grant CSD2009-00046, Grant TEC2013-42937-R, and Grant Project RTC-2014-1847-6.en
• dc.format.mimetype application/pdfca
• dc.identifier.citation Sarnago H, Lucía Ó, Naval A, Burdío JM, Castellví Q, Ivorra A. A versatile multilevel converter platform for cancer treatment using irreversible electroporation. IEEE J Emerg Sel Top Power Electron. 2016;4(1):236-42. doi:10.1109/JESTPE.2015.2512324ca
• dc.identifier.doi http://dx.doi.org/10.1109/JESTPE.2015.2512324
• dc.identifier.issn 2168-6777ca
• dc.identifier.uri http://hdl.handle.net/10230/26153
• dc.language.iso engca
• dc.publisher Institute of Electrical and Electronics Engineers (IEEE)ca
• dc.relation.ispartof IEEE journal of emerging and selected topics in power electronics. 2016;4(1):236-42.
• dc.relation.projectID info:eu-repo/grantAgreement/ES/3PN/CSD2009-00046
• dc.relation.projectID info:eu-repo/grantAgreement/ES/1PE/TEC2013-42937-R
• dc.relation.projectID info:eu-repo/grantAgreement/ES/1PE/RTC-2014-1847-6
• dc.rights © 2016 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works./nThe final published article can be found at http://ieeexplore.ieee.org/stamp/stamp.jsp?tp=&arnumber=7365415ca
• dc.rights.accessRights info:eu-repo/semantics/openAccessca
• dc.subject.keyword Electroporationen
• dc.subject.keyword Multilevel converteren
• dc.subject.keyword Power electronicsen
• dc.title A versatile multilevel converter platform for cancer treatment using irreversible electroporationca
• dc.type info:eu-repo/semantics/articleca
• dc.type.version info:eu-repo/semantics/acceptedVersionca