Estimation of Purkinje trees from electro-anatomical mapping of the left ventricle using minimal cost geodesics
Mostra el registre complet Registre parcial de l'ítem
- dc.contributor.author Cárdenes, Rubén
- dc.contributor.author Sebastián Aguilar, Rafael, 1978-
- dc.contributor.author Soto-Iglesias, David
- dc.contributor.author Berruezo, Antonio
- dc.contributor.author Camara, Oscar
- dc.date.accessioned 2023-11-21T06:54:02Z
- dc.date.available 2023-11-21T06:54:02Z
- dc.date.issued 2015
- dc.description.abstract The electrical activation of the heart is a complex physiological process that is essential for the understanding of several cardiac dysfunctions, such as ventricular tachycardia (VT). Nowadays, patient-specific activation times on ventricular chambers can be estimated from electro-anatomical maps, providing crucial information to clinicians for guiding cardiac radio-frequency ablation treatment. However, some relevant electrical pathways such as those of the Purkinje system are very difficult to interpret from these maps due to sparsity of data and the limited spatial resolution of the system. We present here a novel method to estimate these fast electrical pathways from the local activations maps (LATs) obtained from electro-anatomical maps. The location of Purkinje-myocardial junctions (PMJs) is estimated considering them as critical points of a distance map defined by the activation maps, and then minimal cost geodesic paths are computed on the ventricular surface between the detected junctions. Experiments to validate the proposed method have been carried out in simplified and realistic simulated data, showing good performance on recovering the main characteristics of simulated Purkinje networks (e.g. PMJs). A feasibility study with real cases of fascicular VT was also performed, showing promising results.
- dc.description.sponsorship This work is partially funded by the Sub-programa de Proyectos de Investigación en Salud Instituto de Salud Carlos III, Spain (FIS - PI11/01709), by Spanish Ministry of Economy and Competitiveness (TIN2011-28067 and TIN2012-35874), and by eTorso project (GV/2013/094) from Generalitat Valenciana. The authors thank specially Dr. Bart Bijnens for its comments and suggestions, and Dr. David Andreu and Dr. Juan Fernandez-Armenta for their assistance in the clinical data collection.
- dc.format.mimetype application/pdf
- dc.identifier.citation Cárdenes R, Sebastian R, Soto-Iglesias D, Berruezo A, Camara O. Estimation of Purkinje trees from electro-anatomical mapping of the left ventricle using minimal cost geodesics. Medical Image Analysis. 2015 Aug;24(1):52-62. DOI: 10.1016/j.media.2015.05.007
- dc.identifier.doi http://dx.doi.org/10.1016/j.media.2015.05.007
- dc.identifier.issn 1361-8415
- dc.identifier.uri http://hdl.handle.net/10230/58344
- dc.language.iso eng
- dc.publisher Elsevier
- dc.relation.ispartof Medical Image Analysis. 2015 Aug;24(1):52-62
- dc.relation.projectID info:eu-repo/grantAgreement/ES/3PN/TIN2011-28067
- dc.relation.projectID info:eu-repo/grantAgreement/ES/3PN/TIN2012-35874
- dc.rights © 2015 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
- dc.rights.accessRights info:eu-repo/semantics/openAccess
- dc.rights.uri http://creativecommons.org/licenses/by-nc-nd/4.0/
- dc.subject.keyword Purkinje system
- dc.subject.keyword Minimal cost geodesic paths
- dc.subject.keyword Fast marching
- dc.subject.keyword Singular points
- dc.subject.keyword Electro-anatomical mapping
- dc.subject.keyword Cardiac arrhythmias
- dc.subject.keyword Fascicular ventricular tachycardia
- dc.title Estimation of Purkinje trees from electro-anatomical mapping of the left ventricle using minimal cost geodesics
- dc.type info:eu-repo/semantics/article
- dc.type.version info:eu-repo/semantics/publishedVersion