Powering electronic implants by high frequency volume conduction: in human validation

Mostra el registre complet Registre parcial de l'ítem

• dc.contributor.author Minguillon, Jesus
• dc.contributor.author Tudela Pi, Marc
• dc.contributor.author Becerra Fajardo, Laura
• dc.contributor.author Perera Bel, Enric
• dc.contributor.author Ama, Antonio J. del
• dc.contributor.author Gil-Agudo, Ángel
• dc.contributor.author Megía-García, Álvaro
• dc.contributor.author García-Moreno, Aracelys
• dc.contributor.author Ivorra Cano, Antoni, 1974-
• dc.date.accessioned 2023-03-09T07:25:06Z
• dc.date.available 2023-03-09T07:25:06Z
• dc.date.issued 2023
• dc.description.abstract Objective: Wireless power transfer (WPT) is used as an alternative to batteries to accomplish miniaturization in electronic medical implants. However, established WPT methods require bulky parts within the implant or cumbersome external systems, hindering minimally invasive deployments and the development of networks of implants. As an alternative, we propose a WPT approach based on volume conduction of high frequency (HF) current bursts. These currents are applied through external electrodes and are collected by the implants through two electrodes at their opposite ends. This approach avoids bulky components, enabling the development of flexible threadlike implants. Methods: We study in humans if HF (6.78 MHz) current bursts complying with safety standards and applied through two textile electrodes strapped around a limb can provide substantial powers from pairs of implanted electrodes. Results: Time averaged electric powers obtained from needle electrodes (diameter = 0.4 mm, length = 3 mm, separation = 30 mm) inserted into arms and lower legs of five healthy participants were 5.9 ± 0.7 mW and 2.4 ± 0.3 mW respectively. We also characterize the coupling between the external system and the implants using personalized two-port impedance models generated from medical images. Conclusions: The results demonstrate that innocuous and imperceptible HF current bursts that flow through the tissues by volume conduction can be used to wirelessly power threadlike implants. Significance: This is the first time that WPT based on volume conduction is demonstrated in humans. This method overcomes the limitations of existing WPT methods in terms of minimal invasiveness and usability.
• dc.description.sponsorship This work has received funding from the European Union’s Horizon 2020 research and innovation programme under Grant 779982 (Project EXTEND—Bidirectional Hyper-Connected Neural System). A. Ivorra gratefully acknowledges the financial support by ICREA under the ICREA Academia programme.
• dc.format.mimetype application/pdf
• dc.identifier.citation Minguillon J, Tudela-Pi M, Becerra-Fajardo L, Perera-Bel E, del-Ama AJ, Gil-Agudo Á, Megía-García Á, García-Moreno A, Ivorra A. Powering electronic implants by high frequency volume conduction: in human validation. IEEE Trans Biomed Eng. 2023;70(2):659-70. DOI: 10.1109/TBME.2022.3200409
• dc.identifier.doi http://dx.doi.org/10.1109/TBME.2022.3200409
• dc.identifier.issn 0018-9294
• dc.identifier.uri http://hdl.handle.net/10230/56121
• dc.language.iso eng
• dc.publisher Institute of Electrical and Electronics Engineers (IEEE)
• dc.relation.ispartof IEEE Transactions on Biomedical Engineering. 2023;70(2):659-70.
• dc.relation.projectID info:eu-repo/grantAgreement/EC/H2020/779982
• dc.rights © 2022 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works. http://dx.doi.org/10.1109/TBME.2022.3200409
• dc.rights.accessRights info:eu-repo/semantics/openAccess
• dc.subject.keyword Galvanic coupling
• dc.subject.keyword human validation
• dc.subject.keyword implantable biomedical devices
• dc.subject.keyword volume conduction
• dc.subject.keyword wireless power transfer
• dc.title Powering electronic implants by high frequency volume conduction: in human validation
• dc.type info:eu-repo/semantics/article
• dc.type.version info:eu-repo/semantics/acceptedVersion