High-power short-duration vs. standard radiofrequency cardiac ablation: comparative study based on an in-silico model
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- dc.contributor.author Coderch-Navarro, Sergi
- dc.contributor.author Berjano, Enrique J.
- dc.contributor.author Camara, Oscar
- dc.contributor.author González-Suárez, Ana
- dc.date.accessioned 2021-05-04T09:35:19Z
- dc.date.available 2021-05-04T09:35:19Z
- dc.date.issued 2021
- dc.description.abstract Purpose: While the standard setting during radiofrequency catheter ablation (RFCA) consists of applying low power for long times, a new setting based on high power and short duration (HPSD) has recently been suggested as safer and more effective. Our aim was to compare the electrical and thermal performance of standard vs. HPSD settings, especially to assess the effect of the catheter orientation. Methods: A 3D computational model was built based on a coupled electric-thermal-flow problem. Standard (20 W–45 s and 30 W–30 s) and HPSD settings (70 W–7 s and 90 W–4 s) were compared. Since the model only included a cardiac tissue fragment, the power values were adjusted to 80% of the clinical values (15, 23, 53 and 69 W). Three catheter-tissue orientations were considered (90°, 45° and 0°). Thermal lesions were assessed by the Arrhenius equation. Safety was assessed by checking the occurrence of steam pops (100 °C in tissue) and thrombus formation (80 °C in blood). Results: The computed thermal lesions were in close agreement with the experimental data in the literature, in particular with in vivo studies. HPSD created shallower and wider lesions than standard settings, especially with the catheter at 45°. Steam pops occurred earlier with HPSD, regardless of catheter orientation. Conclusion: HPSD seems to be more effective in cases that need shallow and extensive lesions, especially when the catheter is at 0° or at 45°, as used in pulmonary vein isolation.
- dc.description.sponsorship This work was supported by the Spanish Ministerio de Ciencia, Innovación y Universidades under ‘Programa Estatal de I + D + i Orientada a los Retos de la Sociedad’, Grant Nº ‘RTI2018-094357-B-C21’.
- dc.format.mimetype application/pdf
- dc.identifier.citation Coderch-Navarro S, Berjano E, Camara O, González-Suárez A. High-power short-duration vs. standard radiofrequency cardiac ablation: comparative study based on an in-silico model. Int J Hyperthermia. 2021;38(1):582-92. DOI: 10.1080/02656736.2021.1909148
- dc.identifier.doi http://dx.doi.org/10.1080/02656736.2021.1909148
- dc.identifier.issn 0265-6736
- dc.identifier.uri http://hdl.handle.net/10230/47305
- dc.language.iso eng
- dc.publisher Taylor & Francis
- dc.relation.ispartof International Journal of Hyperthermia. 2021;38(1):582-92
- dc.relation.projectID info:eu-repo/grantAgreement/ES/2PE/RTI2018-094357-B-C21
- dc.rights © 2021 The Author(s). Published with license by Taylor & Francis Group, LLC This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
- dc.rights.accessRights info:eu-repo/semantics/openAccess
- dc.rights.uri http://creativecommons.org/licenses/by/4.0/
- dc.subject.keyword Cardiac ablation
- dc.subject.keyword Computer model
- dc.subject.keyword High-power short-duration settings
- dc.subject.keyword Radiofrequency ablation
- dc.subject.keyword Standard settings
- dc.title High-power short-duration vs. standard radiofrequency cardiac ablation: comparative study based on an in-silico model
- dc.type info:eu-repo/semantics/article
- dc.type.version info:eu-repo/semantics/publishedVersion