Brain simulation as a cloud service: the Virtual Brain on EBRAINS

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• dc.contributor.author Schirner, Michael
• dc.contributor.author Domide, Lia
• dc.contributor.author Perdikis, Dionysios
• dc.contributor.author Triebkorn, Paul
• dc.contributor.author Stefanovski, Leon
• dc.contributor.author Pai, Roopa
• dc.contributor.author Prodan, Paula
• dc.contributor.author Valean, Bogdan
• dc.contributor.author Palmer, Jessica
• dc.contributor.author Langford, Chloê
• dc.contributor.author Blickensdörfer, André
• dc.contributor.author Vlag, Michiel van der
• dc.contributor.author Diaz-Pier, Sandra
• dc.contributor.author Peyser, Alexander
• dc.contributor.author Klijn, Wouter
• dc.contributor.author Pleiter, Dirk
• dc.contributor.author Nahm, Anne
• dc.contributor.author Schmid, Oliver
• dc.contributor.author Woodman, Marmaduke
• dc.contributor.author Zehl, Lyuba
• dc.contributor.author Fousek, Jan
• dc.contributor.author Petkoski, Spase
• dc.contributor.author Kusch, Lionel
• dc.contributor.author Hashemi, Meysam
• dc.contributor.author Marinazzo, Daniele
• dc.contributor.author Mangin, Jean-François
• dc.contributor.author Flöel, Agnes
• dc.contributor.author Akintoye, Simisola
• dc.contributor.author Stahl, Bernd Carsten
• dc.contributor.author Cepic, Michael
• dc.contributor.author Johnson, Emily
• dc.contributor.author Deco, Gustavo
• dc.contributor.author McIntosh, Anthony R.
• dc.contributor.author Hilgetag, Claus C.
• dc.contributor.author Morgan, Marc Alard J.
• dc.contributor.author Schuller, Bernd
• dc.contributor.author Upton, Alex
• dc.contributor.author McMurtrie, Colin
• dc.contributor.author Dickscheid, Timo
• dc.contributor.author Bjaalie, Jan G.
• dc.contributor.author Amunts, Katrin
• dc.contributor.author Mersmann, Jochen
• dc.contributor.author Jirsa, Viktor
• dc.contributor.author Ritter, Petra
• dc.date.accessioned 2023-02-22T07:25:39Z
• dc.date.available 2023-02-22T07:25:39Z
• dc.date.issued 2022
• dc.description.abstract The Virtual Brain (TVB) is now available as open-source services on the cloud research platform EBRAINS (ebrains.eu). It offers software for constructing, simulating and analysing brain network models including the TVB simulator; magnetic resonance imaging (MRI) processing pipelines to extract structural and functional brain networks; combined simulation of large-scale brain networks with small-scale spiking networks; automatic conversion of user-specified model equations into fast simulation code; simulation-ready brain models of patients and healthy volunteers; Bayesian parameter optimization in epilepsy patient models; data and software for mouse brain simulation; and extensive educational material. TVB cloud services facilitate reproducible online collaboration and discovery of data assets, models, and software embedded in scalable and secure workflows, a precondition for research on large cohort data sets, better generalizability, and clinical translation.
• dc.description.sponsorship We acknowledge support by H2020 Research and Innovation Action grants Human Brain Project SGA2 785907, SGA3 945539, ICEI 800858, VirtualBrainCloud 826421 and ERC 683049; Berlin Institute of Health & Foundation Charité, Johanna Quandt Excellence Initiative. Several computations have also been performed on the HPC for Research cluster of the Berlin Institute of Health. We acknowledge the use of Fenix Infrastructure resources, which are partially funded from the European Union's Horizon 2020 research and innovation programme through the ICEI project under the grant agreement No. 800858. German Research Foundation SFB 1436 (project ID 425899996); SFB 1315 (project ID 327654276); SFB 936 (project ID 178316478); SFB-TRR 295 (project ID 424778381); SPP Computational Connectomics RI 2073/6–1, RI 2073/10–2, RI 2073/9–1.
• dc.format.mimetype application/pdf
• dc.identifier.citation Schirner M, Domide L, Perdikis D, Triebkorn P, Stefanovski L, Pai R, Prodan P, Valean B, Palmer J, Langford C, Blickensdörfer A, van der Vlag M, Diaz-Pier S, Peyser A, Klijn W, Pleiter D, Nahm A, Schmid O, Woodman M, Zehl L, Fousek J, Petkoski S, Kusch L, Hashemi M, Marinazzo D, Mangin JF, Flöel A, Akintoye S, Stahl BC, Cepic M, Johnson E, Deco G, McIntosh AR, Hilgetag CC, Morgan M, Schuller B, Upton A, McMurtrie C, Dickscheid T, Bjaalie JG, Amunts K, Mersmann J, Jirsa V, Ritter P. Brain simulation as a cloud service: the Virtual Brain on EBRAINS. Neuroimage. 2022;251:118973. DOI: 10.1016/j.neuroimage.2022.118973
• dc.identifier.doi http://dx.doi.org/10.1016/j.neuroimage.2022.118973
• dc.identifier.issn 1053-8119
• dc.identifier.uri http://hdl.handle.net/10230/55848
• dc.language.iso eng
• dc.publisher Elsevier
• dc.relation.ispartof NeuroImage. 2022;251:118973.
• dc.relation.isreferencedby https://ars.els-cdn.com/content/image/1-s2.0-S1053811922001021-mmc1.docx
• dc.relation.projectID info:eu-repo/grantAgreement/EC/H2020/785907
• dc.relation.projectID info:eu-repo/grantAgreement/EC/H2020/945539
• dc.relation.projectID info:eu-repo/grantAgreement/EC/H2020/800858
• dc.relation.projectID info:eu-repo/grantAgreement/EC/H2020/826421
• dc.relation.projectID info:eu-repo/grantAgreement/EC/H2020/683049
• dc.rights © 2022 The Author(s). Published by Elsevier Inc. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/)
• dc.rights.accessRights info:eu-repo/semantics/openAccess
• dc.rights.uri http://creativecommons.org/licenses/by/4.0/
• dc.subject.keyword Brain modelling
• dc.subject.keyword Cloud
• dc.subject.keyword Connectome
• dc.subject.keyword Neuroimaging
• dc.subject.keyword Network model
• dc.subject.keyword High performance computing
• dc.subject.keyword Reproducibility
• dc.subject.keyword Data protection
• dc.title Brain simulation as a cloud service: the Virtual Brain on EBRAINS
• dc.type info:eu-repo/semantics/article
• dc.type.version info:eu-repo/semantics/publishedVersion