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Impact of a partial smoke-free legislation on myocardial infarction incidence, mortality and case-fatality in a population-based registry: the REGICOR study

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dc.contributor.author Agüero, Fernando H., 1968-
dc.contributor.author Dégano, Irene R.
dc.contributor.author Subirana, Isaac
dc.contributor.author Grau, Maria
dc.contributor.author Zamora, Alberto
dc.contributor.author Sala, Joan
dc.contributor.author Ramos, Rafel
dc.contributor.author Tresserras i Gaju, Ricard, 1957-
dc.contributor.author Elosua Llanos, Roberto
dc.date.accessioned 2023-02-13T08:56:09Z
dc.date.available 2023-02-13T08:56:09Z
dc.date.issued 2013
dc.identifier.citation Agüero F, Dégano IR, Subirana I, Grau M, Zamora A, Sala J, et al. Impact of a partial smoke-free legislation on myocardial infarction incidence, mortality and case-fatality in a population-based registry: the REGICOR study. PLoS ONE. 2013 Jan 23;8(1):e53722. DOI: 10.1371/journal.pone.0053722
dc.identifier.issn 1932-6203
dc.identifier.uri http://hdl.handle.net/10230/55736
dc.description.abstract Coronary heart disease (CHD) is the leading cause of death, and smoking its strongest modifiable risk factor. Our aim was to determine the impact of the Spanish 2006 partial smoke-free legislation on acute myocardial infarction (AMI) incidence, hospitalization and mortality rates, and 28-day case-fatality in Girona, Spain. Using a population-based registry (the REGICOR Study), we compared population incidence, hospitalization, and mortality rates, and 28-day case-fatality in the pre- and post-ban periods (2002–2005 and 2006–2008, respectively) by binomial regression analysis adjusted for confounding factors. We also analyzed the ban's impact on the outcomes of interest using the AMI definitions of the American Heart Association (AHA)/European Society of Cardiology (ESC) and the World Health Organization (WHO)-Monitoring trends and determinants in cardiovascular diseases (MONICA). In the post-ban period, AMI incidence and mortality rates significantly decreased (relative risk [RR] = 0.89; 95% confidence interval [CI] = 0.81–0.97 and RR = 0.82; 95% CI = 0.71–0.94, respectively). Incidence and mortality rates decreased in both sexes, especially in women, and in people aged 65–74 years. Former and non-smokers (passive smokers) showed diminished incidence rates. Implementation of the ban was not associated with AMI case-fatality. Models tended to be more significant with the WHO-MONICA than with the AHA/ESC definition. The 2006 Spanish partial smoke-free legislation was associated with a decrease in population AMI incidence and mortality, particularly in women, in people aged 65–74 years, and in passive smokers. These results clarify the association between AMI mortality and the enactment of a partial smoke-free legislation and reinforce the effectiveness of smoking regulations in preventing CHD.
dc.format.mimetype application/pdf
dc.language.iso eng
dc.publisher Public Library of Science (PLoS)
dc.relation.ispartof PLoS ONE. 2013 Jan 23;8(1):e53722
dc.rights ©2013 Agüero et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
dc.rights.uri http://creativecommons.org/licenses/by/4.0/
dc.subject.other Tabac -- Dret i legislació
dc.subject.other Miocardi -- Malalties
dc.subject.other Mortalitat
dc.subject.other Hàbit de fumar
dc.subject.other Infart de miocardi
dc.title Impact of a partial smoke-free legislation on myocardial infarction incidence, mortality and case-fatality in a population-based registry: the REGICOR study
dc.type info:eu-repo/semantics/article
dc.identifier.doi http://dx.doi.org/10.1371/journal.pone.0053722
dc.rights.accessRights info:eu-repo/semantics/openAccess
dc.type.version info:eu-repo/semantics/publishedVersion

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