Impact of a partial smoke-free legislation on myocardial infarction incidence, mortality and case-fatality in a population-based registry: the REGICOR study

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  • dc.contributor.author Agüero, Fernando H., 1968-
  • dc.contributor.author Dégano, Irene R.
  • dc.contributor.author Subirana, Isaac
  • dc.contributor.author Grau, Maria
  • dc.contributor.author Zamora, Alberto
  • dc.contributor.author Sala, Joan
  • dc.contributor.author Ramos, Rafel
  • dc.contributor.author Tresserras i Gaju, Ricard, 1957-
  • dc.contributor.author Elosua Llanos, Roberto
  • dc.date.accessioned 2023-02-13T08:56:09Z
  • dc.date.available 2023-02-13T08:56:09Z
  • dc.date.issued 2013
  • dc.description.abstract Coronary heart disease (CHD) is the leading cause of death, and smoking its strongest modifiable risk factor. Our aim was to determine the impact of the Spanish 2006 partial smoke-free legislation on acute myocardial infarction (AMI) incidence, hospitalization and mortality rates, and 28-day case-fatality in Girona, Spain. Using a population-based registry (the REGICOR Study), we compared population incidence, hospitalization, and mortality rates, and 28-day case-fatality in the pre- and post-ban periods (2002–2005 and 2006–2008, respectively) by binomial regression analysis adjusted for confounding factors. We also analyzed the ban's impact on the outcomes of interest using the AMI definitions of the American Heart Association (AHA)/European Society of Cardiology (ESC) and the World Health Organization (WHO)-Monitoring trends and determinants in cardiovascular diseases (MONICA). In the post-ban period, AMI incidence and mortality rates significantly decreased (relative risk [RR] = 0.89; 95% confidence interval [CI] = 0.81–0.97 and RR = 0.82; 95% CI = 0.71–0.94, respectively). Incidence and mortality rates decreased in both sexes, especially in women, and in people aged 65–74 years. Former and non-smokers (passive smokers) showed diminished incidence rates. Implementation of the ban was not associated with AMI case-fatality. Models tended to be more significant with the WHO-MONICA than with the AHA/ESC definition. The 2006 Spanish partial smoke-free legislation was associated with a decrease in population AMI incidence and mortality, particularly in women, in people aged 65–74 years, and in passive smokers. These results clarify the association between AMI mortality and the enactment of a partial smoke-free legislation and reinforce the effectiveness of smoking regulations in preventing CHD.
  • dc.format.mimetype application/pdf
  • dc.identifier.citation Agüero F, Dégano IR, Subirana I, Grau M, Zamora A, Sala J, et al. Impact of a partial smoke-free legislation on myocardial infarction incidence, mortality and case-fatality in a population-based registry: the REGICOR study. PLoS ONE. 2013 Jan 23;8(1):e53722. DOI: 10.1371/journal.pone.0053722
  • dc.identifier.doi http://dx.doi.org/10.1371/journal.pone.0053722
  • dc.identifier.issn 1932-6203
  • dc.identifier.uri http://hdl.handle.net/10230/55736
  • dc.language.iso eng
  • dc.publisher Public Library of Science (PLoS)
  • dc.relation.ispartof PLoS ONE. 2013 Jan 23;8(1):e53722
  • dc.rights ©2013 Agüero et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
  • dc.rights.accessRights info:eu-repo/semantics/openAccess
  • dc.rights.uri http://creativecommons.org/licenses/by/4.0/
  • dc.subject.other Tabac -- Dret i legislació
  • dc.subject.other Miocardi -- Malalties
  • dc.subject.other Mortalitat
  • dc.subject.other Hàbit de fumar
  • dc.subject.other Infart de miocardi
  • dc.title Impact of a partial smoke-free legislation on myocardial infarction incidence, mortality and case-fatality in a population-based registry: the REGICOR study
  • dc.type info:eu-repo/semantics/article
  • dc.type.version info:eu-repo/semantics/publishedVersion