Recerca: articles, congressos, llibres

Enviaments recents

  • Benjet, Corina; Alonso Caballero, Jordi; Koenen, Karestan C. (Cambridge University Press, 2016)
    BACKGROUND: Considerable research has documented that exposure to traumatic events has negative effects on physical and mental health. Much less research has examined the predictors of traumatic event exposure. Increased ...
  • Kuhlwilm, Martin; Prado Martínez, Javier, 1987-; Lalueza Fox, Carles, 1965-; Marquès i Bonet, Tomàs, 1975-; Castellano Hereza, Sergi (Nature Research, 2016)
    It has been shown that Neanderthals contributed genetically to modern humans outside Africa 47,000-65,000 years ago. Here we analyse the genomes of a Neanderthal and a Denisovan from the Altai Mountains in Siberia together ...
  • Creixell, Pau; Gonzalez-Perez, Abel; López Bigas, Núria; Mutation Consequences and Pathway Analysis Working Group of the International Cancer Genome Consortium (Nature Research, 2015)
    Genomic information on tumors from 50 cancer types cataloged by the International Cancer Genome Consortium (ICGC) shows that only a few well-studied driver genes are frequently mutated, in contrast to many infrequently ...
  • Orozco, Carlos Alberto; Martínez Bosch, Neus; Enrique Guerrero, Pedro; Vinaixa, Judith; Dalotto-Moreno, Tomás; Iglesias García, Mar; Moreno, Mireia; Djurec, Magdolna; Poirier, Françoise; Gabius, Hans J.; Fernández-Zapico, Martin E.; Hwang, Rosa F.; Guerra, Carmen; Rabinovich, Gabriel A.; Navarro Medrano, Pilar (National Academy of Sciences, 2018)
    Pancreatic ductal adenocarcinoma (PDA) remains one of the most lethal tumor types, with extremely low survival rates due to late diagnosis and resistance to standard therapies. A more comprehensive understanding of the ...
  • Rubio Martínez, Mercedes, 1980-; Bustamante Pineda, Mariona; Hernandez-Ferrer, Carles, 1987-; Fernández-Orth, Dietmar; Pantano Rubiño, Lorena, 1982-; Sarria-Trujillo, Yaris; Piqué-Borras, Maria; Vellve del Amo, Kilian; Agramunt, Silvia; Carreras Collado, Ramón; Estivill, Xavier, 1955-; González Ruiz, Juan Ramón; Mayor, Alfredo (Public Library of Science (PLoS), 2018)
    Circulating small RNAs, including miRNAs but also isomiRs and other RNA species, have the potential to be used as non-invasive biomarkers for communicable and non-communicable diseases. This study aims to characterize and ...
  • Werzowa, Johannes M.; Säemann, Marcus D.; Mohl, Alexander; Bergmann, Michael; Kaltenecker, Christopher C.; Brozek, Wolfgang; Thomas, Andreas; Haidinger, Michael; Antlanger, Marlies; Kovarik, Johannes J.; Kopecky, Chantal; Song, Peter X. K.; Budde, Klemens; Pascual Santos, Julio; Hecking, Manfred (Public Library of Science (PLoS), 2018)
    Treating hyperglycemia in previously non-diabetic individuals with exogenous insulin immediately after kidney transplantation reduced the odds of developing Posttransplantation Diabetes Mellitus (PTDM) in our previous ...
  • Herrera Boyer, Perfecto; Serra, Xavier; Peeters, Geoffroy (1999)
    Sound content description is one of the aims of the MPEG-7 initiative. Although MPEG-7 focuses on indexing and retrieval of audio, there are other sound content-based processing applications waiting to be developed once ...
  • Amarasinghe, Ishari; Hernández Leo, Davinia; Manathunga, Kalpani; Jonsson, Anders, 1973- (Graz University of Technology. Institut für Informationssysteme und Computer Medien (IICM), 2018)
    Collaborative learning spaces deployed in Massive Open Online Courses (MOOCs) provide productive social learning opportunities. However, sustaining collaboration in these spaces is challenging. This paper provides a ...
  • Gotsens, Mercè; Marí-Dell'Olmo, Marc; Pérez, Katherine; Palència, Laia; Martinez-Beneito, Miguel-Angel; Rodríguez-Sanz, Maica; Burström, Bo; Costa, Giuseppe; Deboosere, Patrick; Domínguez-Berjón, Felicitas; Dzúrová, Dagmar; Gandarillas, Ana; Hoffmann, Rasmus; Kovacs, Katalin; Marinacci, Chiara; Martikainen, Pekka; Pikhart, Hynek; Rosicova, Katarina; Saez, Marc; Santana, Paula; Riegelnig, Judith; Schwierz, Cornelia; Tarkiainen, Lasse; Borrell i Thió, Carme (Elsevier, 2013)
    This study analysed socioeconomic inequalities in mortality due to injuries in small areas of 15 European cities, by sex, at the beginning of this century. A cross-sectional ecological study with units of analysis being ...
  • Farré, Lídia; González, Libertad; Ortega, Francesc (De Gruyter, 2011)
    We investigate the effect of immigration on the labor supply of skilled women, using data on Spain’s large recent immigration wave. We adopt a spatial correlations approach and instrument for current immigration using ...
  • Albó, Laia; Hernández Leo, Davinia; Moreno Oliver, Verónica (Taylor & Francis, 2018)
    This paper explores how the use of smartphones vs. laptops influences students’ engagement, behaviour and experience watching academic videos in a collaborative classroom. Experiments were run in authentic teaching sessions ...
  • Martí-Pastor, Marc; Pont, Àngels; Ávila, Mónica; Garin Boronat, Olatz, 1979-; Vilagut Saiz, Gemma, 1975-; Forero, Carlos G.; Pardo Cladellas, Yolanda; Tresserras i Gaju, Ricard, 1957-; Medina-Bustos, Antonia; Garcia-Codina, Oriol; Cabasés, Juan; Rajmil Rajmil, Luis Alberto; Alonso Caballero, Jordi; Ferrer Forés, Maria Montserrat (BioMed Central, 2018)
    Background: The EQ-5D has been frequently used in national health surveys. This study is a head-to-head comparison to assess how expanding the number of levels from three (EQ-5D-3L) to five in the new EQ-5D-5L version has ...
  • Saravia, Rocío; Ten-Blanco, Marc; Julià Hernández, Marina; Gagliano, Humberto; Andero, Raül; Armario García, Antonio; Maldonado, Rafael, 1961-; Berrendero Díaz, Fernando, 1971- (Elsevier, 2019)
    Δ9-tetrahydrocannabinol (THC) consumption during adolescence is reported to be a risk factor for the appearance of psychiatric disorders later in life. The interaction between genetic or environmental events and cannabinoid ...
  • Saravia, Rocío; Ten-Blanco, Marc; Grande, María T.; Maldonado, Rafael, 1961-; Berrendero Díaz, Fernando, 1971- (Elsevier, 2019)
    Nicotine withdrawal is associated with cognitive deficits including attention, working memory, and episodic memory impairments. These cognitive deficits are a hallmark of nicotine abstinence which could be targeted in order ...
  • Marcuello, María; Mayol Girbau, Xavier; Felipe-Fumero, Eloísa; Costa, Jaume; López-Hierro, Laia; Salvans Ruiz, Silvia; Alonso Gonçalves, Sandra; Pascual Damieta, Marta; Grande Posa, Luís; Pera Roman, Miguel; Peritoneal infection after colorectal cancer surgery is associated with a higher rate of tumor relapse. We have recently proposed that soluble inflammatory factors released in response to a postoperative infection enhance tumor progression features in residual tumor cells. In an effort to set up models to study the mechanisms of residual tumor cell activation during surgery-associated inflammation, we have analyzed the phenotypic response of colon cancer cell lines to the paracrine effects of THP-1 and U937 differentiated human macrophages, which release an inflammatory medium characteristic of an innate immune response. The exposure of the colon cancer cell lines HT-29 and SW620 to conditioned media isolated from differentiated THP-1 and U937 macrophages induced a mesenchymal-like phenotypic shift, involving the activation of in vitro invasiveness. The inflammatory media activated the β-catenin/TCF4 transcriptional pathway and induced the expression of several mesenchymal (e.g., FN1 and VIM) and TCF4 target genes (e.g., MMP7, PTGS2, MET, and CCD1). Similarly, differential expression of some transcription factors involved in epithelial-to-mesenchymal transitions (i.e. ZEB1, SNAI1, and SNAI2) was variably observed in the colon cancer cell lines when exposed to the inflammatory media. THP-1 and U937 macrophages, which displayed characteristics of M1 differentiation, overexpressed some cytokines previously shown to be induced in colorectal cancer patients with increased rates of tumor recurrence associated with postoperative peritoneal infections, thus suggesting their pro-tumoral character. Therefore, the environment created by inflammatory M1 macrophages enhances features of epithelial-to-mesenchymal transition, and may be useful as a model to characterize pro-inflammatory cytokines as putative biomarkers of tumor recurrence risk. (Public Library of Science (PLoS), 2018)
  • Paul, Tanja; Salazar Degracia, Anna; Peinado, Victor I.; Tura-Ceide, Olga; Blanco, Isabel; Barreiro Portela, Esther; Barberà, Joan Albert (Public Library of Science (PLoS), 2018)
    OBJECTIVE: Soluble guanylate cyclase (sGC) is a key enzyme of the nitric oxide-cyclic guanosine 3',5'-monophosphate (NO-cGMP) signaling pathway, and its pharmacological stimulation has been shown to prevent the development ...
  • Merino, Irene; Porter, Stephen B.; Johnston, Brian D.; Clabots, Connie; Shaw, Evelyn; Horcajada Gallego, Juan Pablo; Cantón, Rafael; Ruiz-Garbajosa, Patricia; Johnson, James R.; ITUBRAS-GEIH group (Public Library of Science (PLoS), 2017)
    OBJECTIVE: To assess experimental virulence among sequence type 131 (ST131) Escherichia coli bloodstream isolates in relation to virulence genotype and subclone. METHODS: We analysed 48 Spanish ST131 bloodstream isolates ...
  • Sordo, Mohamed; Oramas, Sergio; Espinosa-Anke, Luis (Springer, 2015)
    This paper presents a method for the generation of struc- tured data sources for music recommendation using information extracted from unstructured text sources. The proposed method identi es entities in text that are ...
  • Toro Soto, Juan Manuel, 1976- (Konrad Lorenz Fundación Universitaria, 2011)
    Uno de los mayores problemas en el estudio del lenguaje es la comprensión de sus fundamentos biológicos. Una forma de abordar este problema que ha resultado efectiva es la de estudiar hasta qué punto compartimos con otros ...
  • Broquetas, Teresa; Garcia-Retortillo, Montserrat; Hernández, Juanjo; Puigvehí, Marc; Cañete Hidalgo, Nuria; Coll Estrada, Susanna; Cabrero Daniel, Beatriz; Giménez Romaní, Maria Dolors; Solà Lamoglia, Ricard; Carrión Rodríguez, José Antonio (Public Library of Science (PLoS), 2017)
    BACKGROUND: HBeAg-negative chronic hepatitis B patients require long-term nucleos(t)ide analogues(NAs) because loss of surface antigen (HBsAg) is unusual. Low quantitative HBsAg (qHBsAg) levels can identify patients with ...

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