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Myocardial injury as a prognostic factor in mid- and long-term follow-up of COVID-19 survivors

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dc.contributor.author Izquierdo, Andrea
dc.contributor.author Mojón Álvarez, Diana
dc.contributor.author Bardají, Alfredo
dc.contributor.author Carrasquer, Anna
dc.contributor.author Calvo-Fernández, Alicia
dc.contributor.author Carreras-Mora, José
dc.contributor.author Giralt, Teresa
dc.contributor.author Pérez-Fernández, Silvia
dc.contributor.author Farré López, Núria
dc.contributor.author Soler, Cristina
dc.contributor.author Solà-Richarte, Clàudia
dc.contributor.author Cabero, Paula
dc.contributor.author Vaquerizo Montilla, Beatriz
dc.contributor.author Marrugat de la Iglesia, Jaume
dc.contributor.author Ribas Barquet, Núria
dc.date.accessioned 2022-09-30T05:51:07Z
dc.date.available 2022-09-30T05:51:07Z
dc.date.issued 2021
dc.identifier.citation Izquierdo A, Mojón D, Bardají A, Carrasquer A, Calvo-Fernández A, Carreras-Mora J, Giralt T, Pérez-Fernández S, Farré N, Soler C, Solà-Richarte C, Cabero P, Vaquerizo B, Marrugat J, Ribas N. Myocardial injury as a prognostic factor in mid- and long-term follow-up of COVID-19 survivors. J Clin Med. 2021 Dec 16;10(24):5900. DOI: 10.3390/jcm10245900
dc.identifier.issn 2077-0383
dc.identifier.uri http://hdl.handle.net/10230/54228
dc.description.abstract Myocardial injury, which is present in >20% of patients hospitalized for COVID-19, is associated with increased short-term mortality, but little is known about its mid- and long-term consequences. We evaluated the association between myocardial injury with one-year mortality and readmission in 172 COVID-19 patients discharged alive. Patients were grouped according to the presence or absence of myocardial injury (defined by hs-cTn levels) on admission and matched by age and sex. We report mortality and hospital readmission at one year after admission in all patients and echocardiographic, laboratory and clinical data at six months in a subset of 86 patients. Patients with myocardial injury had a higher prevalence of hypertension (73.3% vs. 50.0%, p = 0.003), chronic kidney disease (10.5% vs. 2.35%, p = 0.06) and chronic heart failure (9.3% vs. 1.16%, p = 0.03) on admission. They also had higher mortality or hospital readmissions at one year (11.6% vs. 1.16%, p = 0.01). Additionally, echocardiograms showed thicker walls in these patients (10 mm vs. 8 mm, p = 0.002) but without functional disorder. Myocardial injury in COVID-19 survivors is associated with poor clinical prognosis at one year, independent of age and sex, but not with echocardiographic functional abnormalities at six months.
dc.format.mimetype application/pdf
dc.language.iso eng
dc.publisher MDPI
dc.relation.ispartof J Clin Med. 2021 Dec 16;10(24):5900
dc.rights © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
dc.rights.uri https://creativecommons.org/licenses/by/4.0/
dc.title Myocardial injury as a prognostic factor in mid- and long-term follow-up of COVID-19 survivors
dc.type info:eu-repo/semantics/article
dc.identifier.doi http://dx.doi.org/10.3390/jcm10245900
dc.subject.keyword COVID-19
dc.subject.keyword Long-term
dc.subject.keyword Mortality
dc.subject.keyword Myocardial injury
dc.subject.keyword Prognosis
dc.subject.keyword Readmission
dc.rights.accessRights info:eu-repo/semantics/openAccess
dc.type.version info:eu-repo/semantics/publishedVersion


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