Myocardial injury as a prognostic factor in mid- and long-term follow-up of COVID-19 survivors

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• dc.contributor.author Izquierdo, Andrea
• dc.contributor.author Mojón Álvarez, Diana
• dc.contributor.author Bardají, Alfredo
• dc.contributor.author Carrasquer, Anna
• dc.contributor.author Calvo-Fernández, Alicia
• dc.contributor.author Carreras-Mora, José
• dc.contributor.author Giralt Borrell, Teresa
• dc.contributor.author Pérez-Fernández, Silvia
• dc.contributor.author Farré López, Núria
• dc.contributor.author Soler, Cristina
• dc.contributor.author Solà-Richarte, Clàudia
• dc.contributor.author Cabero, Paula
• dc.contributor.author Vaquerizo Montilla, Beatriz
• dc.contributor.author Marrugat de la Iglesia, Jaume
• dc.contributor.author Ribas Barquet, Núria
• dc.date.accessioned 2022-09-30T05:51:07Z
• dc.date.available 2022-09-30T05:51:07Z
• dc.date.issued 2021
• dc.description.abstract Myocardial injury, which is present in >20% of patients hospitalized for COVID-19, is associated with increased short-term mortality, but little is known about its mid- and long-term consequences. We evaluated the association between myocardial injury with one-year mortality and readmission in 172 COVID-19 patients discharged alive. Patients were grouped according to the presence or absence of myocardial injury (defined by hs-cTn levels) on admission and matched by age and sex. We report mortality and hospital readmission at one year after admission in all patients and echocardiographic, laboratory and clinical data at six months in a subset of 86 patients. Patients with myocardial injury had a higher prevalence of hypertension (73.3% vs. 50.0%, p = 0.003), chronic kidney disease (10.5% vs. 2.35%, p = 0.06) and chronic heart failure (9.3% vs. 1.16%, p = 0.03) on admission. They also had higher mortality or hospital readmissions at one year (11.6% vs. 1.16%, p = 0.01). Additionally, echocardiograms showed thicker walls in these patients (10 mm vs. 8 mm, p = 0.002) but without functional disorder. Myocardial injury in COVID-19 survivors is associated with poor clinical prognosis at one year, independent of age and sex, but not with echocardiographic functional abnormalities at six months.
• dc.format.mimetype application/pdf
• dc.identifier.citation Izquierdo A, Mojón D, Bardají A, Carrasquer A, Calvo-Fernández A, Carreras-Mora J, Giralt T, Pérez-Fernández S, Farré N, Soler C, Solà-Richarte C, Cabero P, Vaquerizo B, Marrugat J, Ribas N. Myocardial injury as a prognostic factor in mid- and long-term follow-up of COVID-19 survivors. J Clin Med. 2021 Dec 16;10(24):5900. DOI: 10.3390/jcm10245900
• dc.identifier.doi http://dx.doi.org/10.3390/jcm10245900
• dc.identifier.issn 2077-0383
• dc.identifier.uri http://hdl.handle.net/10230/54228
• dc.language.iso eng
• dc.publisher MDPI
• dc.relation.ispartof J Clin Med. 2021 Dec 16;10(24):5900
• dc.rights © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
• dc.rights.accessRights info:eu-repo/semantics/openAccess
• dc.rights.uri https://creativecommons.org/licenses/by/4.0/
• dc.subject.keyword COVID-19
• dc.subject.keyword Long-term
• dc.subject.keyword Mortality
• dc.subject.keyword Myocardial injury
• dc.subject.keyword Prognosis
• dc.subject.keyword Readmission
• dc.title Myocardial injury as a prognostic factor in mid- and long-term follow-up of COVID-19 survivors
• dc.type info:eu-repo/semantics/article
• dc.type.version info:eu-repo/semantics/publishedVersion