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dc.contributor.author Crespo Barrio, Marta
dc.contributor.author Pérez-Sáez, María José
dc.contributor.author Redondo Pachón, María Dolores
dc.contributor.author Llinàs-Mallol, Laura
dc.contributor.author Montero, Maria Milagro
dc.contributor.author Villar García, Judit
dc.contributor.author Arias Cabrales, Carlos Enrique
dc.contributor.author Burballa Tàrrega, Carla, 1988-
dc.contributor.author Vázquez, Susana
dc.contributor.author Mir, Marisa
dc.contributor.author Sierra Ochoa, Adriana
dc.contributor.author Collado Nieto, Silvia
dc.contributor.author Barrios Barrera, Clara
dc.contributor.author Rodriguez García, Eva
dc.contributor.author Sans Atxer, Laia
dc.contributor.author Barbosa Puig, Francisco
dc.contributor.author Cao Baduell, Higinio
dc.contributor.author Arenas Jiménez, María Dolores
dc.contributor.author Güerri Fernández, Roberto
dc.contributor.author Horcajada Gallego, Juan Pablo
dc.contributor.author Pascual Santos, Julio
dc.date.accessioned 2020-11-19T08:21:57Z
dc.date.available 2020-11-19T08:21:57Z
dc.date.issued 2020
dc.identifier.citation Crespo M, Pérez-Sáez MJ, Redondo-Pachón D, Llinàs-Mallol L, Montero MM, Villar-García J. et al. COVID-19 in elderly kidney transplant recipients. Am J Transplant. 2020 Oct; 20(10): 2883-89. DOI: 10.1111/ajt.16096
dc.identifier.issn 1600-6135
dc.identifier.uri http://hdl.handle.net/10230/45810
dc.description.abstract The SARS-Cov-2 infection disease (COVID-19) pandemic has posed at risk the kidney transplant (KT) population, particularly the elderly recipients. From March 12 until April 4, 2020, we diagnosed COVID-19 in 16 of our 324 KT patients aged ≥65 years old (4.9%). Many of them had had contact with healthcare facilities in the month prior to infection. Median time of symptom onset to admission was 7 days. All presented with fever and all but one with pneumonia. Up to 33% showed renal graft dysfunction. At infection diagnosis, mTOR inhibitors or mycophenolate were withdrawn. Tacrolimus was withdrawn in 70%. The main treatment combination was hydroxychloroquine and azithromycin. A subset of patients was treated with anti-retroviral and tocilizumab. Short-term fatality rate was 50% at a median time since admission of 3 days. Those who died were more frequently obese, frail, and had underlying heart disease. Although a higher respiratory rate was observed at admission in nonsurvivors, symptoms at presentation were similar between both groups. Patients who died were more anemic, lymphopenic, and showed higher D-dimer, C-reactive protein, and IL-6 at their first tests. COVID-19 is frequent among the elderly KT population and associates a very early and high mortality rate.
dc.format.mimetype application/pdf
dc.language.iso eng
dc.publisher Wiley
dc.rights This is the peer reviewed version of the following article: Crespo M, Pérez-Sáez MJ, Redondo-Pachón D, Llinàs-Mallol L, Montero MM, Villar-García J. et al. COVID-19 in elderly kidney transplant recipients. Am J Transplant. 2020 Oct; 20(10): 2883-89, which has been published in final form at http://dx.doi.org/10.1111/ajt.16096. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.
dc.title COVID-19 in elderly kidney transplant recipients
dc.type info:eu-repo/semantics/article
dc.identifier.doi http://dx.doi.org/10.1111/ajt.16096
dc.subject.keyword Clinical research/practice
dc.subject.keyword Infection and infectious agents - viral
dc.subject.keyword Kidney transplantation/nephrology
dc.subject.keyword Patient survival
dc.rights.accessRights info:eu-repo/semantics/openAccess
dc.type.version info:eu-repo/semantics/acceptedVersion

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