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Risk factors associated with major complications after ultrasound-guided percutaneous renal biopsy of native kidneys

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dc.contributor.author Pombas, Beatriz
dc.contributor.author Sánchez Parrila, Juan
dc.contributor.author Radosevic, Aleksandar
dc.contributor.author Gimeno Beltran, Javier
dc.contributor.author Busto Barrera, Marcos
dc.contributor.author Barrios Barrera, Clara
dc.contributor.author Sans Atxer, Laia
dc.contributor.author Pascual Santos, Julio
dc.contributor.author Soler, María José
dc.date.accessioned 2020-06-11T07:14:43Z
dc.date.available 2020-06-11T07:14:43Z
dc.date.issued 2020
dc.identifier.citation Pombas B, Rodríguez E, Sánchez J, Radosevic A, Gimeno J, Busto M, et al. Risk factors associated with major complications after ultrasound-guided percutaneous renal biopsy of native kidneys. Kidney Blood Press Res. 2020; 45(1):122-30. DOI: 10.1159/000504544
dc.identifier.issn 1420-4096
dc.identifier.uri http://hdl.handle.net/10230/44953
dc.description.abstract Introduction: Percutaneous renal biopsy (PRB) of native kidneys is an important tool for diagnosis and management of renal disease. In this study, we analyzed the success, safety, and risk complications of PRB in our center. Methods: A retrospective review of ultrasound-guided PRB done at our institution from January 1998 to December 2017 was performed. Clinical and laboratory data were collected for 661 PRBs. Statistical analysis was performed using the Mann-Whitney U test for continuous variable and chi-square test for categorical variables. Multivariate analysis using logistic regression was performed to assess factors associated with increased risk of complications after PRB. Results: The median age was 56 (42-68) years old, the majority were male (64%) and white (82%). Ten glomeruli were present in 63.5% of PRBs. Overall, the rate of complications was 16.6%, where 15.1% of them were minor complications and 1.5% were major complications. Perinephritic hematoma accounted for the minor complication that occurred most frequently, whereas the need of a blood transfusion was the prevalent for major complications. By multivariate analysis, increased activated partial thromboplastin time (aPTT; OR 1.11, 95% CI 1.035-1.180) and prebiopsy lower hemoglobin (Hgb; OR 1.61, 95% CI 1.086-2.304) were identified as independent risk factors for major complications. In addition, older patients (OR 1.057, 95% CI 1.001-1.117) were identified as an independent risk factor for blood transfusion requirement. Conclusion: The current risk of complications after native PRB is low. Major complications are most common in case of increased aPTT and decreased Hgb baseline level.
dc.format.mimetype application/pdf
dc.language.iso eng
dc.publisher Karger (S. Karger AG)
dc.rights This article is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (CC BY-NC-ND) (http://www.karger.com/Services/OpenAccessLicense). https://creativecommons.org/licenses/by/4.0/. Usage and distribution for commercial purposes as well as any distribution of modified material requires written permission.
dc.rights.uri https://creativecommons.org/licenses/by/4.0/
dc.title Risk factors associated with major complications after ultrasound-guided percutaneous renal biopsy of native kidneys
dc.type info:eu-repo/semantics/article
dc.identifier.doi http://dx.doi.org/10.1159/000504544
dc.subject.keyword Bleeding
dc.subject.keyword Complications risk
dc.subject.keyword Kidney disease
dc.subject.keyword Renal biopsy
dc.rights.accessRights info:eu-repo/semantics/openAccess
dc.type.version info:eu-repo/semantics/publishedVersion


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