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Welcome to the UPF Digital Repository

The institutional repository collects, disseminates and preserves, in digital form, the intellectual output that results from the academic and research activity of the UPF and also the scientific magazines and the institutional publications. Its purpose is to increase the impact of research done at the UPF and its intellectual memory.

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Metabolite identification in drug discovery : from data to information and from information to knowledge

Cece, Esra Nurten, 1984- (Universitat Pompeu Fabra, 2017-03-03)

Drug metabolism studies provide the opportunity to enhance metabolic properties of new drugs. The overall aims of the drug metabolism studies are to (1.) optimize pharmacokinetic properties of the drug candidates, (2.) ...
The Aurora B-dependent NoCut checkpoint prevents damage of anaphase bridges after DNA replication stress

Amaral, Nuno (Universitat Pompeu Fabra, 2016-01-22)

La coordinació de la citocinesis amb la segregació cromosòmica és essencial per mantenir l’estabilitat cromosòmica durant la proliferació cel•lular. Tant en llevat com en cèl•lules animals, els ponts de cromatina en anafase ...
Understanding ligand-receptor recognition by means of high-throughput molecular dynamics : a perspective for drug discovery

Ferruz Capapey, Noelia 1988- (Universitat Pompeu Fabra, 2016-03-04)

Understanding how receptor-ligand interactions occur is a first step towards designing new drugs. The complete reconstruction of the binding process in a drug-receptor system provides all the physical-chemistry variables ...
La introducción del Estado regulador y la administración independiente en España : el impulso del Derecho de la Unión Europea y las transformaciones del Derecho Público Español

Solanes Mullor, Joan (Universitat Pompeu Fabra, 2014-07-02)

En las dos últimas décadas, el Estado regulador y su aparato institucional han experimentado un decisivo impulso en Europa. Tanto la Unión Europa -mediante agencies- como los Estados Miembros -con la creación de organismos ...
Tandem repeat variation in human and great ape populations and its impact on gene expression divergence

Carvalho, Tiago Loureiro de, 1987- (Universitat Pompeu Fabra, 2016-01-21)

Genetic variation in humans and the great apes has been amply explored using a wide variety of markers, among them tandem repeats (TRs). Because of the nature of TRs, highly variable in length due to its high mutation rate, ...