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L'étude consiste à analyser la langue algérienne, dite dialecte algérien, afin d'observer son fonctionnement au sein de la société algérienne. Le dialecte algérien est une langue nationale, utilisée par les interlocuteurs dans la vie quotidienne, une variété peu étudiée même si son usage est primordial et courant (Chachou, 2008; Kerras et Baya, 2017, 2016; Ibrahimi, 2004, etc.).
L'objectif de notre étude est de démontrer une fois de plus que le dialecte algérien est une langue à part entière (Kerras et Baya, 2018), car chaque pays a le droit et le devoir non seulement d'utiliser sa langue maternelle dans les domaines domestiques, mais aussi au sein de l'éducation afin d'éviter la discrimination et l'exclusion sociale (Amorós Negre, 2014). Pour ces raisons une étude complémentaire est réalisée afin d'observer l'usage de la langue algérienne dans les contextes audiovisuels, plus précisément, en tenant compte des sous-titres.
(2020) Kerras, Nassima; Essayahi, Moulay Lahssan BayaApplied pharmacogenetics to predict response to treatment of first psychotic episode: study protocol
The application of personalized medicine in patients with first-episode psychosis (FEP) requires tools for classifying patients according to their response to treatment, considering both treatment efficacy and toxicity. However, several limitations have hindered its translation into clinical practice. Here, we describe the rationale, aims and methodology of Applied Pharmacogenetics to Predict Response to Treatment of First Psychotic Episode (the FarmaPRED-PEP project), which aims to develop and validate predictive algorithms to classify FEP patients according to their response to antipsychotics, thereby allowing the most appropriate treatment strategy to be selected. These predictors will integrate, through machine learning techniques, pharmacogenetic (measured as polygenic risk scores) and epigenetic data together with clinical, sociodemographic, environmental, and neuroanatomical data. To do this, the FarmaPRED-PEP project will use data from two already recruited cohorts: the PEPS cohort from the "Genotype-Phenotype Interaction and Environment. Application to a Predictive Model in First Psychotic Episodes" study (the PEPs study from the Spanish abbreviation) (N=335) and the PAFIP cohort from "Clinical Program on Early Phases of Psychosis" (PAFIP from the Spanish abbreviation) (N = 350). These cohorts will be used to create the predictor, which will then be validated in a new cohort, the FarmaPRED cohort (N = 300). The FarmaPRED-PEP project has been designed to overcome several of the limitations identified in pharmacogenetic studies in psychiatry: (1) the sample size; (2) the phenotype heterogeneity and its definition; (3) the complexity of the phenotype and (4) the gender perspective. The global reach of the FarmaPRED-PEP project is to facilitate the effective deployment of precision medicine in national health systems.
(2025) Mas, Sergi; Julià, Laura; Cuesta, Manuel J.; Crespo-Facorro, Benedicto; Vázquez-Bourgon, Javier; Spuch, Carlos; González-Pinto, Ana; Ibáñez, Ángela; Usall, Judith; Romero-López-Alberca, Cristina; Catalan, Ana; Mané Santacana, Anna; Bernardo, MiquelBackground: This study aimed to evaluate the incidence of lymphadenopathies after COVID-19 vaccination and their impact on the clinical management of gynecologic oncology patients. Methods: A retrospective observational study was conducted involving patients who underwent abdominopelvic or thoracoabdominopelvic CT scans during diagnosis or follow-up. Patients were classified into a vaccinated group (Vac group) and a non-vaccinated group (NoVac group). The radiological appearance of lymphadenopathies was categorized as low or high risk of malignancy, and management strategies were recorded as standard management or additional assessment. Results: 75 patients were included, with 44 in the Vac group and 31 in the NoVac group. The incidence of lymphadenopathies was similar between the groups: 34.1% in the Vac group and 32.3% in the NoVac group (p = 0.868). High-risk lymphadenopathies were observed in 20.4% of the Vac group and 22.6% of the NoVac group, while low-risk lymphadenopathies were seen in 13.6% of the Vac group and 9.7% of the NoVac group (p = 0.691). Standard management was the most common approach, used in 80.0% of the Vac group and 100.0% of the NoVac group (p = 0.25). Conclusions: COVID-19 vaccine does not increase the incidence of lymphadenopathies in imaging tests of gynecological cancer patients.
(2024) Fernandez Sanahuja, Laura; Miralpeix, Ester; Solé Sedeño, Josep Maria; Baucells, Marta; Fabregó, Berta; Sierra, Ana; Mancebo Moreno, GemmaLa confianza es un aspecto básico en el trabajo diario de las plataformas de fact-checking. Este valor sustenta las relaciones que mantienen con dos actores clave en el proceso periodístico: las fuentes informativas y las audiencias. Partiendo de los discursos de confianza (Manninen, 2017) y de la transparencia participativa (Karlsson, 2010), el objetivo de este estudio es analizar las relaciones que establecen las plataformas de fact-checking independientes hacia sus fuentes, por un lado, y sus audiencias, por otro. Para ello, se realiza un análisis de contenido cualitativo de las páginas web de 18 iniciativas de 18 países y seis entrevistas en profundidad a editores/as y/o periodistas de seis de los proyectos analizados. Entre los resultados obtenidos, se observa cómo las plataformas encarnan un discurso de confianza pragmático en el uso de las fuentes, con las oficiales y las expertas como las más utilizadas. Además, otorgan una alta confianza a su audiencia, a la que introducen en el proceso de producción periodístico, y ponen en marcha numerosas acciones de alfabetización mediática, una línea de trabajo con un alto potencial.
(2024) Mauri, Marcel, 1977-; Chaparro-Domínguez, María-Ángeles; Rodríguez Martínez, Ruth, 1976-Purpose: To address the educational gaps and support needs of patients with low anterior resection syndrome (LARS) following rectal cancer surgery. The LARSCAT project aimed to develop comprehensive resources to better inform patients and enhance their quality of life. Methods: A qualitative study was conducted between November 2022 and March 2023. Seven focus groups were formed, including six patients, two surgeons, and three nurses. Patients had undergone rectal cancer surgery with stoma reversal 2 to 12 years earlier, and all experienced major LARS. The focus groups, held in-person and online, explored the impact on daily life, social and sexual health, mood, rest, and relationships. Thematic analysis was performed to identify key issues and support strategies following the COREQ guidelines. Results: Participants reported insufficient information regarding potential dysfunctions after rectal cancer surgery, and difficulties finding reliable information online. The timing of receiving information varied according to individual coping mechanisms. LARS symptoms significantly impacted daily life, social activities, sexual health, and mood. Patients emphasised the need for more tailored information and supplementary written materials to read at their own pace. Consequently, three comprehensive documents were created and made available online. Conclusion: This study highlights a significant gap in patient education on the long-term effects of rectal cancer surgery. The resources developed by the LARSCAT project aim to provide essential support to patients and healthcare professionals. Future research should focus on integrating these resources into routine care and evaluating their impact on patient outcomes and quality of life.
(2024) Ribas, Yolanda; Muñoz-Duyos, Arantxa; Franquet, Marta; Guerreiro, Isabel; Perau, Jordi; Porras, Oscar; Rodríguez, Dolores; Rojo, Jorge; Ramírez, Lucía; Rubio, Mercè; Marinello, Franco; Jiménez-Toscano, Marta; Romero, Clara