Bienvenidos al Repositorio Digital de la UPF

El repositorio institucional recoge, difunde y preserva la producción intelectual en formato digital que resulta de la actividad académica e investigadora de la UPF, las revistas científicas y las publicaciones institucionales. Su finalidad es contribuir a aumentar el impacto de la investigación hecha en la UPF y preservar la memoria intelectual de la UPF.

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Añadido Recientemente

  • Pogoryelova, Oksana; Wilson, Ian J.; Mansbach, Hank; Argov, Zohar; Nishino, Ichizo; Lochmüller, Hanns (Wolters Kluwer (LWW), 2019)
    Objective: To test the hypothesis that common GNE mutations influence disease severity; using statistical analysis of patient cohorts from different countries. Methods: Systematic literature review identified 11 articles ...
  • Bolognesi, Benedetta; Faure, Andre J.; Seuma, Mireia; Schmiedel, Jörn M.; Tartaglia, Gian Gaetano; Lehner, Ben, 1978- (Nature Research, 2019)
    Insoluble protein aggregates are the hallmarks of many neurodegenerative diseases. For example, aggregates of TDP-43 occur in nearly all cases of amyotrophic lateral sclerosis (ALS). However, whether aggregates cause ...
  • Chammas, Paul, 1992-; Mocavini, Ivano; Di Croce, Luciano (Nature Research, 2020)
    Polycomb repressive complex 2 (PRC2) is a key epigenetic multiprotein complex involved in the regulation of gene expression in metazoans. PRC2 is formed by a tetrameric core that endows the complex with histone methyltransferase ...
  • Blanco, Enrique; González Ramírez, Mar; Alcaine Colet, Anna, 1992-; Aranda Aragón, Sergio; Di Croce, Luciano (Elsevier, 2020)
    An intricate molecular machinery is at the core of gene expression regulation in every cell. During the initial stages of organismal development, the coordinated activation of diverse transcriptional programs is crucial ...
  • Lucic, Bojana; Chen, Heng-Chang; Kuzman, Maja; Zorita, Eduard; Wegner, Julia; Minneker, Vera; Wang, Wei; Fronza, Raffaele; Laufs, Stefanie; Schmidt, Manfred; Stadhouders, Ralph; Roukos, Vassilis; Vlahovicek, Kristian; Filion, Guillaume; Lusic, Marina (Nature Research, 2019)
    HIV-1 recurrently targets active genes and integrates in the proximity of the nuclear pore compartment in CD4+ T cells. However, the genomic features of these genes and the relevance of their transcriptional activity for ...

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