PURPOSE To assess the effectiveness and safety of computed tomography (CT)-guided cryoablation for treating adrenal metastases (AMs). METHODS This study included 12 patients treated with 13 CT-guided cryoablation procedures for AMs between 2016 and 2020. Patients were selected based on specific criteria, including tumor size ¿5 cm and suitability for surgery. Procedures were performed by expert radiologists, with comprehensive monitoring for complications and regular post-treatment evaluations. RESULTS The primary technical success rate was 91.7%, with a secondary success rate of 100% following repeat procedures. Over an 8¿24-month follow-up period, local tumor recurrence was observed in 16.7% of patients, and systemic progression occurred in five (41.6%) patients. The average overall survival duration was 26.4 ± 5.6 months. CONCLUSION CT-guided cryoablation is a feasible and effective treatment option for AMs, demonstrating high technical success rates and manageable complications. CLINICAL SIGNIFICANCE This study highlights CT-guided cryoablation as a promising treatment for AMs, offering a mini-mally invasive alternative to surgery with good local control and safety profile. Further research, including multi-center studies, is needed to confirm these findings.
