Bienvenidos al Repositorio Digital de la UPF

El repositorio institucional recoge, difunde y preserva la producción intelectual en formato digital que resulta de la actividad académica e investigadora de la UPF, las revistas científicas y las publicaciones institucionales. Su finalidad es contribuir a aumentar el impacto de la investigación hecha en la UPF y preservar la memoria intelectual de la UPF.

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Añadido Recientemente

  • Guns or butter: vidas, guerras y estado de bienestar
    Callejón, María; Guix i Oliver, Joan; Ortún Rubio, Vicente (2024-09)
    Al analizar el vínculo entre guerras y salud de la población, surge la cuestión de si las guerras entre estados han influido o no, o en qué medida, en el desarrollo y enorme logro social del estado de bienestar avanzado ...
  • The Wnt-dependent master regulator NKX1-2 controls mouse pre-implantation development
    Nakagawa, Shoma; Carnevali, Davide; Tan, Xiangtian; Alvarez, Mariano J.; Parfitt, David-Emlyn; Di Vicino, Umberto; Arumugam, Karthik; Shin, William; Aranda, Sergi; Normanno, Davide; Sebastián Pérez, Rubén; Cannatá, Chiara; Cortes, Paola; Neguembor, Maria Victoria; Shen, Michael M.; Califano, Andrea; Cosma, Maria Pia (Elsevier, 2024)
    Embryo size, specification, and homeostasis are regulated by a complex gene regulatory and signaling network. Here we used gene expression signatures of Wnt-activated mouse embryonic stem cell (mESC) clones to reverse ...
  • TANGO1 inhibitors reduce collagen secretion and limit tissue scarring
    Raote, Ishier; Häkkinen, Hanna-Maria; Vibe, Carine; Broadbent, Katrina; Carolis, Carlo; Ruprecht, Verena; Malhotra, Vivek (Nature Research, 2024)
    Uncontrolled secretion of ECM proteins, such as collagen, can lead to excessive scarring and fibrosis and compromise tissue function. Despite the widespread occurrence of fibrotic diseases and scarring, effective therapies ...
  • Active transcription and epigenetic reactions synergistically regulate meso-scale genomic organization
    Kant, Aayush; Guo, Zixian; Vinayak, Vinayak; Neguembor, Maria Victoria; Li, Wing Shun; Agrawal, Vasundhara; Pujadas, Emily; Almassalha, Luay; Backman, Vadim; Lakadamyali, Melike; Cosma, Maria Pia; Shenoy, Vivek B. (Nature Research, 2024)
    In interphase nuclei, chromatin forms dense domains of characteristic sizes, but the influence of transcription and histone modifications on domain size is not understood. We present a theoretical model exploring this ...
  • Developing a platform for secretion of biomolecules in Mycoplasma feriruminatoris
    Gonzalez de Miguel, Javier; Montero-Blay, Ariadna, 1994-; Ciampi, Ludovica; Rodriguez-Arce, Irene; Serrano Pubull, Luis, 1982- (BioMed Central, 2024)
    Background: Having a simple and fast dividing organism capable of producing and exposing at its surface or secreting functional complex biomolecules with disulphide bridges is of great interest. The mycoplasma bacterial ...

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