A new tool to screen patients with severe obstructive sleep apnea in the primary care setting: a prospective multicenter study

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  • dc.contributor.author Peñacoba, Patricia
  • dc.contributor.author Llauger, M. Antònia
  • dc.contributor.author Fortuna, Ana M.
  • dc.contributor.author Flor, Xavier
  • dc.contributor.author Sampol, Gabriel
  • dc.contributor.author Pedro Pijoan, Anna María
  • dc.contributor.author Grau Sanmartí, Núria, 1974-
  • dc.contributor.author Santiveri, Carme
  • dc.contributor.author Juvanteny, Joan
  • dc.contributor.author Aoiz, José Ignacio
  • dc.contributor.author Bayó, Joan
  • dc.contributor.author Lloberes, Patricia
  • dc.contributor.author Mayos, Mercè
  • dc.contributor.author PASHOS Working Group
  • dc.date.accessioned 2022-08-01T14:23:27Z
  • dc.date.available 2022-08-01T14:23:27Z
  • dc.date.issued 2022
  • dc.description.abstract Background: The coordination between different levels of care is essential for the management of obstructive sleep apnea (OSA). The objective of this multicenter project was to develop a screening model for OSA in the primary care setting. Methods: Anthropometric data, clinical history, and symptoms of OSA were recorded in randomly selected primary care patients, who also underwent a home sleep apnea test (HSAT). Respiratory polygraphy or polysomnography were performed at the sleep unit to establish definite indication for continuous positive airway pressure (CPAP). By means of cross-validation, a logistic regression model (CPAP yes/no) was designed, and with the clinical variables included in the model, a scoring system was established using the β coefficients (PASHOS Test). In a second stage, results of HSAT were added, and the final accuracy of the model was assessed. Results: 194 patients completed the study. The clinical test included the body mass index, neck circumference and observed apneas during sleep (AUC 0.824, 95% CI 0.763-0.886, P < 0.001). In a second stage, the oxygen desaturation index (ODI) of 3% (ODI3% ≥ 15%) from the HSAT was added (AUC 0.911, 95% CI 0.863-0.960, P < 0.001), with a sensitivity of 85.5% (95% CI 74.7-92.1) and specificity of 67.8% (95% CI 55.1-78.3). Conclusions: The use of this model would prevent referral to the sleep unit for 55.1% of the patients. The two-stage PASHOS model is a useful and practical screening tool for OSA in primary care for detecting candidates for CPAP treatment. Clinical Trial Registration Registry: ClinicalTrials.gov; Name: PASHOS Project: Advanced Platform for Sleep Apnea Syndrome Assessment; URL: https://clinicaltrials.gov/ct2/show/NCT02591979 ; Identifier: NCT02591979. Date of registration: October 30, 2015.
  • dc.format.mimetype application/pdf
  • dc.identifier.citation Peñacoba P, Llauger MA, Fortuna AM, Flor X, Sampol G, Pedro-Pijoan AM, Grau N, Santiveri C, Juvanteny J, Aoiz JI, Bayó J, Lloberes P, Mayos M; PASHOS Working Group. A new tool to screen patients with severe obstructive sleep apnea in the primary care setting: a prospective multicenter study. BMC Pulm Med. 2022 Jan 15;22(1):38. DOI: 10.1186/s12890-022-01827-0
  • dc.identifier.doi http://dx.doi.org/10.1186/s12890-022-01827-0
  • dc.identifier.issn 1471-2466
  • dc.identifier.uri http://hdl.handle.net/10230/53900
  • dc.language.iso eng
  • dc.publisher BioMed Central
  • dc.relation.ispartof BMC Pulm Med. 2022 Jan 15;22(1):38
  • dc.rights © The Author(s) 2022. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
  • dc.rights.accessRights info:eu-repo/semantics/openAccess
  • dc.rights.uri http://creativecommons.org/licenses/by/4.0/
  • dc.subject.keyword Continuous positive airway pressure (CPAP)
  • dc.subject.keyword Home sleep apnea test
  • dc.subject.keyword Obstructive sleep apnea
  • dc.subject.keyword Primary healthcare
  • dc.subject.keyword Screening model
  • dc.subject.keyword Sleep unit
  • dc.title A new tool to screen patients with severe obstructive sleep apnea in the primary care setting: a prospective multicenter study
  • dc.type info:eu-repo/semantics/article
  • dc.type.version info:eu-repo/semantics/publishedVersion

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