Association between socioeconomic deprivation and colorectal cancer screening outcomes: Low uptake rates among the most and least deprived people
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- dc.contributor.author Buron Pust, Andreaca
- dc.contributor.author Augé, Josep M.ca
- dc.contributor.author Sala Serra, Mariaca
- dc.contributor.author Román, Martaca
- dc.contributor.author Castells, Antonica
- dc.contributor.author Macià Guilà, Francesc Assísca
- dc.contributor.author Comas Serrano, Mercèca
- dc.contributor.author Guiriguet, Carolinaca
- dc.contributor.author Bessa Caserras, Xavierca
- dc.contributor.author Castells, Xavierca
- dc.contributor.author PROCOLON research groupca
- dc.date.accessioned 2018-07-17T07:34:13Z
- dc.date.available 2018-07-17T07:34:13Z
- dc.date.issued 2017
- dc.description.abstract BACKGROUND: Screening with faecal occult blood tests reduces colorectal cancer-related mortality; however, age, sex and socioeconomic factors affect screening outcomes and could lead to unequal mortality benefits. The aim of this study was to describe the main outcomes of the population-based Barcelona colorectal cancer screening programme (BCRCSP) by deprivation. METHODS: Retrospective study of the eligible population of the first round of the BCRCSP. Participants' postal addresses were linked with the MEDEA database to obtain the deprivation quintiles (Dq). Chi-squared tests were used to compare proportions across variables and logistic regression was used to estimate the adjusted effects of age, sex and deprivation on uptake, FIT positivity, colonoscopy adherence and advanced neoplasia detection rate. RESULTS: Overall uptake was 44.7%, higher in Dq2, 3 and 4 (OR 1.251, 1.250 and 1.276, respectively) than in the least deprived quintile (Dq 1), and lowest in Dq5 (OR 0.84). Faecal immunochemical test (FIT) positivity and the percentage of people with detectable faecal haemoglobin below the positivity threshold increased with deprivation. The advanced neoplasia detection rate was highest in Dq4. CONCLUSION: Unlike most regions where inequalities are graded along the socioeconomic continuum, inequalities in the uptake of colorectal cancer screening in Spain seem to be concentrated first in the most disadvantaged group and second in the least deprived group. The correlation of deprivation with FIT-positivity and faecal haemoglobin below the positivity threshold is worrying due to its association with colorectal cancer and overall mortality.
- dc.format.mimetype application/pdf
- dc.identifier.citation Buron A, Auge JM, Sala M, Román M, Castells A, Macià F. et al. Association between socioeconomic deprivation and colorectal cancer screening outcomes: Low uptake rates among the most and least deprived people. PLoS One. 2017 Jun 16;12(6):e0179864. DOI: 10.1371/journal.pone.0179864
- dc.identifier.doi http://dx.doi.org/10.1371/journal.pone.0179864
- dc.identifier.issn 1932-6203
- dc.identifier.uri http://hdl.handle.net/10230/35170
- dc.language.iso eng
- dc.publisher Public Library of Science (PLoS)ca
- dc.relation.ispartof PLoS One. 2017 Jun 16;12(6):e0179864
- dc.rights Copyright © 2017 Buron et al. This is an open access article distributed under the terms of the https://creativecommons.org/licenses/by/4.0/, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
- dc.rights.accessRights info:eu-repo/semantics/openAccess
- dc.rights.uri https://creativecommons.org/licenses/by/4.0/
- dc.subject.other Còlon -- Càncer -- Prevenció
- dc.title Association between socioeconomic deprivation and colorectal cancer screening outcomes: Low uptake rates among the most and least deprived peopleca
- dc.type info:eu-repo/semantics/article
- dc.type.version info:eu-repo/semantics/publishedVersion