Malnutrition according to GLIM criteria is associated with mortality and hospitalizations in rehabilitation patients with stable chronic obstructive pulmonary disease
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- dc.contributor.author Dávalos Yerovi, Vanesa
- dc.contributor.author Marco Navarro, Ester
- dc.contributor.author Sánchez-Rodríguez, María Dolores
- dc.contributor.author Duran Jordà, Xavier, 1974-
- dc.contributor.author Meza Valderrama, Delky
- dc.contributor.author Rodríguez, Diego
- dc.contributor.author Muñoz, Elena
- dc.contributor.author Tejero Sánchez, Marta
- dc.contributor.author Muns, Maria Dolors
- dc.contributor.author Guillén-Solà, Anna
- dc.contributor.author Duarte Oller, Esther
- dc.date.accessioned 2021-07-08T06:51:17Z
- dc.date.available 2021-07-08T06:51:17Z
- dc.date.issued 2021
- dc.description.abstract Malnutrition has a negative impact on patients with chronic pulmonary obstructive disease (COPD). The purpose of this study was to assess the prevalence of malnutrition, defined by the Global Leadership Initiative for Malnutrition (GLIM), in stable COPD patients referred to pulmonary rehabilitation, and to explore potential associations of malnutrition according to GLIM, and its components, with increased risk of mortality and hospitalizations in 2 years. In a post-hoc analysis of a prospective cohort of 200 rehabilitation patients with stable COPD, main outcome variables were hospital admissions, length of stay, and mortality during a 2-year follow-up. Covariates were malnutrition according to GLIM and its phenotypic criteria: unintentional weight loss, low body mass index (BMI), and low fat-free mass (FFM). Univariate and multivariate analysis were performed using logistic and proportional hazard Cox regression. Malnutrition according to GLIM showed 45% prevalence and was associated with increased mortality risk. Low age-related BMI and FFM were independently associated with mortality, which persisted after adjustment for age and lung function. Malnutrition and low BMI were also associated with increased risk of hospitalization. Malnutrition according to GLIM criteria was highly prevalent in rehabilitation patients with COPD and was associated with nearly 3 times greater mortality and hospitalization risk.
- dc.format.mimetype application/pdf
- dc.identifier.citation Dávalos-Yerovi V, Marco E, Sánchez-Rodríguez D, Duran X, Meza-Valderrama D, Rodríguez DA, Muñoz E, Tejero-Sánchez M, Muns MD, Guillén-Solà A, Duarte E. Malnutrition according to GLIM criteria is associated with mortality and hospitalizations in rehabilitation patients with stable chronic obstructive pulmonary disease. Nutrients. 2021;13(2):369. DOI: 10.3390/nu13020369
- dc.identifier.doi http://dx.doi.org/10.3390/nu13020369
- dc.identifier.issn 2072-6643
- dc.identifier.uri http://hdl.handle.net/10230/48111
- dc.language.iso eng
- dc.publisher MDPI
- dc.relation.ispartof Nutrients. 2021;13(2):369
- dc.rights © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
- dc.rights.accessRights info:eu-repo/semantics/openAccess
- dc.rights.uri http://creativecommons.org/licenses/by/4.0/
- dc.subject.keyword GLIM
- dc.subject.keyword Chronic pulmonary obstructive disease
- dc.subject.keyword Hospitalization
- dc.subject.keyword Malnutrition
- dc.subject.keyword Mortality
- dc.subject.keyword Rehabilitation
- dc.title Malnutrition according to GLIM criteria is associated with mortality and hospitalizations in rehabilitation patients with stable chronic obstructive pulmonary disease
- dc.type info:eu-repo/semantics/article
- dc.type.version info:eu-repo/semantics/publishedVersion