Risk factors and effectiveness of preventive measures against influenza in the community

Castilla, Jesús; Godoy i García, Pere; Domínguez García, Àngela; Martín, Vicente; Delgado Rodríguez, Miguel; Martínez Baz, Iván; Baricot, Maretva; Soldevila, Núria; Mayoral, José María; Astray, Jenaro; Quintana, José María; Cantón, Rafael; Castro, Ady; González Candela, Fernando; Alonso Caballero, Jordi; Sáez, Marc; Tamames, Sonia; Pumarola, Tomás; CIBERESP Cases and Controls in Pandemic Influenza Working Group

Risk factors and effectiveness of preventive measures against influenza in the community

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dc.contributor.author Castilla, Jesúsca
dc.contributor.author Godoy i García, Pereca
dc.contributor.author Domínguez García, Àngelaca
dc.contributor.author Martín, Vicenteca
dc.contributor.author Delgado Rodríguez, Miguelca
dc.contributor.author Martínez Baz, Ivánca
dc.contributor.author Baricot, Maretvaca
dc.contributor.author Soldevila, Núriaca
dc.contributor.author Mayoral, José Maríaca
dc.contributor.author Astray, Jenaroca
dc.contributor.author Quintana, José Maríaca
dc.contributor.author Cantón, Rafaelca
dc.contributor.author Castro, Adyca
dc.contributor.author González Candela, Fernandoca
dc.contributor.author Alonso Caballero, Jordica
dc.contributor.author Sáez, Marcca
dc.contributor.author Tamames, Soniaca
dc.contributor.author Pumarola, Tomásca
dc.contributor.author CIBERESP Cases and Controls in Pandemic Influenza Working Groupca
dc.date.accessioned 2015-12-02T14:08:58Z
dc.date.available 2015-12-02T14:08:58Z
dc.date.issued 2013
dc.description.abstract BACKGROUND: The role of different risk exposures and preventive measures against influenza has not been well established. OBJECTIVE: The aim of this study was to evaluate risk factors and measures to prevent influenza infection in the community. METHODS: We conducted a multicenter case-control study. Cases were 481 outpatients aged 18 years or older with laboratory-confirmed influenza A(H1N1)09 in the 2009-2010 season in Spain. A control was selected for each case from outpatients from the same area matched by age and date of consultation. Information on risk situations, preventive measures and other variables was obtained by interview and review of the medical record. RESULTS: In the multivariate conditional logistic regression analysis, the risk of a diagnosis of influenza increased with the number of cohabitants (compared with <3 cohabitants, three cohabitants had an OR= 1·80, 95% CI 1·12-2·89, and ≥5 cohabitants had an OR = 2·66, 95% CI 1·31-5·41) and for health care workers (OR = 2·94, 95% CI 1·53-5·66). The use of metropolitan public transport was associated with a lower frequency of a diagnosis of influenza (OR = 0·45, 95% CI 0·30-0·68) but not the use of taxis or long-distance transport. The influenza A(H1N1)09 vaccine had a protective effect (OR =0·13, 95% CI 0·04-0·48), unlike hand washing after touching contaminated surfaces or the use of alcohol-based hand sanitizers. CONCLUSION: The home environment appears to play an important role in the spread of influenza in adults, but not the use of public transport. Health care workers have a higher risk of contracting influenza. Vaccination was the most effective preventive measure.ca
dc.format.mimetype application/pdfca
dc.identifier.citation Castilla J, Godoy P, Domínguez Á, Martín V, Delgado-Rodríguez M, Martínez-Baz I et al. Risk factors and effectiveness of preventive measures against influenza in the community. Influenza and other respiratory viruses. 2013. 7(2): 177-183. DOI 10.1111/j.1750-2659.2012.00361.xca
dc.identifier.doi http://dx.doi.org/10.1111/j.1750-2659.2012.00361.x
dc.identifier.issn 1750-2640
dc.identifier.uri http://hdl.handle.net/10230/25308
dc.language.iso engca
dc.publisher Wileyca
dc.relation.ispartof Influenza and other respiratory viruses. 2013. 7(2): 177-183
dc.rights All articles published in this journal are made available under the terms of the Creative Commons License.ca
dc.rights.accessRights info:eu-repo/semantics/openAccessca
dc.subject.keyword Epidemiology
dc.subject.keyword Infection control
dc.subject.keyword Influenza
dc.subject.keyword Public health
dc.subject.keyword Transmission
dc.subject.keyword Vaccine
dc.subject.other Gripca
dc.subject.other Vacunesca
dc.subject.other Epidemiologiaca
dc.title Risk factors and effectiveness of preventive measures against influenza in the communityca
dc.type info:eu-repo/semantics/articleca
dc.type.version info:eu-repo/semantics/publishedVersionca

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