Clinical profiles in renal patients with COVID-19
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- dc.contributor.author Arenas Jiménez, María Dolores
- dc.contributor.author Crespo Barrio, Marta
- dc.contributor.author Pérez-Sáez, María José
- dc.contributor.author Collado Nieto, Silvia
- dc.contributor.author Redondo Pachón, María Dolores
- dc.contributor.author Llinàs-Mallol, Laura
- dc.contributor.author Montero, Maria Milagro
- dc.contributor.author Villar García, Judit
- dc.contributor.author Arias Cabrales, Carlos Enrique
- dc.contributor.author Barbosa Puig, Francisco
- dc.contributor.author Buxeda, Anna
- dc.contributor.author Burballa Tàrrega, Carla, 1988-
- dc.contributor.author Sans Atxer, Laia
- dc.contributor.author Vázquez, Susana
- dc.contributor.author Oliveras, Anna
- dc.contributor.author Mir, Marisa
- dc.contributor.author Outón González, Sara
- dc.contributor.author Galceran Herrera, Isabel
- dc.contributor.author Solà Porta, Eulàlia
- dc.contributor.author Sierra Ochoa, Adriana
- dc.contributor.author Barrios Barrera, Clara
- dc.contributor.author Rodriguez García, Eva
- dc.contributor.author Cao Baduell, Higinio
- dc.date.accessioned 2021-10-15T07:17:10Z
- dc.date.available 2021-10-15T07:17:10Z
- dc.date.issued 2020
- dc.description.abstract The COVID-19 pandemic has led to frequent referrals to the emergency department on suspicion of this infection in maintenance hemodialysis (MHD) and kidney transplant (KT) patients. We aimed to describe their clinical features comparing confirmed and suspected non-confirmed COVID-19 cases during the Spanish epidemic peak. Confirmed COVID-19 ((+)COVID-19) corresponds to patient with positive RT-PCR SARS-CoV-2 assay. Non-confirmed COVID-19 ((-)COVID-19) corresponds to patients with negative RT-PCR. COVID-19 was suspected in 61 patients (40/803 KT (4.9%), 21/220 MHD (9.5%)). Prevalence of (+)COVID-19 was 3.2% in KT and 3.6% in MHD patients. Thirty-four (26 KT and 8 MHD) were (+)COVID-19 and 27 (14 KT and 13 MHD) (-)COVID-19. In comparison with (-)COVID-19 patients, (+)COVID-19 showed higher frequency of typical viral symptoms (cough, dyspnea, asthenia and myalgias), pneumonia (88.2% vs. 14.3%) and LDH and CRP while lower phosphate levels, need of hospital admission (100% vs. 63%), use of non-invasive mechanical ventilation (36% vs. 11%) and mortality (38% vs. 0%) (p < 0.001). Time from symptoms onset to admission was longer in patients who finally died than in survivors (8.5 vs. 3.8, p = 0.007). In KT and MHD patients, (+)COVID-19 shows more clinical severity than suspected non-confirmed cases. Prompt RT-PCR is mandatory to confirm COVID-19 diagnosis.
- dc.format.mimetype application/pdf
- dc.identifier.citation Arenas MD, Crespo M, Pérez-Sáez MJ, Collado S, Redondo-Pachón D, Llinàs-Mallol L et al. Clinical profiles in renal patients with COVID-19. J Clin Med. 2020 Aug 18; 9(8):2665. DOI: 10.3390/jcm9082665
- dc.identifier.doi http://dx.doi.org/10.3390/jcm9082665
- dc.identifier.issn 2077-0383
- dc.identifier.uri http://hdl.handle.net/10230/48666
- dc.language.iso eng
- dc.publisher MDPI
- dc.rights Copyright © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/)
- dc.rights.accessRights info:eu-repo/semantics/openAccess
- dc.rights.uri http://creativecommons.org/licenses/by/4.0/
- dc.subject.keyword COVID-19
- dc.subject.keyword RT-PCR
- dc.subject.keyword SARS-CoV-2
- dc.subject.keyword Hemodialysis
- dc.subject.keyword Kidney transplantation
- dc.subject.keyword Pneumonia
- dc.title Clinical profiles in renal patients with COVID-19
- dc.type info:eu-repo/semantics/article
- dc.type.version info:eu-repo/semantics/publishedVersion