A synthetic microbial Daisyworld: planetary regulation in the test tube

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• dc.contributor.author Maull, Victor
• dc.contributor.author Pla Mauri, Jordi
• dc.contributor.author Conde Pueyo, Núria, 1983-
• dc.contributor.author Solé Vicente, Ricard, 1962-
• dc.date.accessioned 2025-03-31T06:19:23Z
• dc.date.available 2025-03-31T06:19:23Z
• dc.date.issued 2024
• dc.description.abstract The idea that the Earth system self-regulates in a habitable state was proposed in the 1970s by James Lovelock, who conjectured that life plays a self-regulatory role on a planetary-level scale. A formal approach to such hypothesis was presented afterwards under a toy model known as the Daisyworld. The model showed how such life-geosphere homeostasis was an emergent property of the system, where two species with different properties adjusted their populations to the changing external environment. So far, this ideal world exists only as a mathematical or computational construct, but it would be desirable to have a real, biological implementation of Lovelock's picture beyond our one biosphere. Inspired by the exploration of synthetic ecosystems using genetic engineering and recent cell factory designs, here we propose a possible implementation for a microbial Daisyworld. This includes: (i) an explicit proposal for an engineered design of a two-strain consortia, using pH as the external, abiotic control parameter and (ii) several theoretical and computational case studies including two, three and multiple species assemblies. The special alternative implementations and their implications in other synthetic biology scenarios, including ecosystem engineering, are outlined.
• dc.description.sponsorship This work was funded by grant nos. FIS2016-77447-R MINECO/AEI/FEDER, and AGAUR 2021 SGR 00751. J.P.M. has been funded by the PRE2020-091968 grant from the Spanish government.
• dc.format.mimetype application/pdf
• dc.identifier.citation Maull V, Pla Mauri J, Conde Pueyo N, Solé R. A synthetic microbial Daisyworld: planetary regulation in the test tube. J R Soc Interface. 2024 Feb;21(211):20230585. DOI: 10.1098/rsif.2023.0585
• dc.identifier.doi http://dx.doi.org/10.1098/rsif.2023.0585
• dc.identifier.issn 1742-5689
• dc.identifier.uri http://hdl.handle.net/10230/70044
• dc.language.iso eng
• dc.publisher Royal Society
• dc.relation.ispartof J R Soc Interface. 2024 Feb;21(211):20230585
• dc.relation.projectID info:eu-repo/grantAgreement/ES/1PE/FIS2016-77447-R
• dc.relation.projectID info:eu-repo/grantAgreement/ES/2PE/PRE2020-091968
• dc.rights © 2024 The Authors. Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/, which permits unrestricted use, provided the original author and source are credited.
• dc.rights.accessRights info:eu-repo/semantics/openAccess
• dc.rights.uri http://creativecommons.org/licenses/by/4.0/
• dc.subject.keyword Daisyworld
• dc.subject.keyword Earth systems science
• dc.subject.keyword Homeostasis
• dc.subject.keyword Synthetic biology
• dc.subject.keyword Terraformation
• dc.title A synthetic microbial Daisyworld: planetary regulation in the test tube
• dc.type info:eu-repo/semantics/article
• dc.type.version info:eu-repo/semantics/publishedVersion