Comparison of treatment outcomes in severe personality disorder patients with or without substance use disorders: a 36-month prospective pragmatic follow-up study.

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  • dc.contributor.author Lana, Fernandoca
  • dc.contributor.author Sánchez-Gil, Carmenca
  • dc.contributor.author Adroher, Núria D.ca
  • dc.contributor.author Pérez Solá, Victorca
  • dc.contributor.author Feixas, Guillemca
  • dc.contributor.author Martí-Bonany, Josepca
  • dc.contributor.author Torrens, Martaca
  • dc.date.accessioned 2016-12-16T11:10:34Z
  • dc.date.available 2016-12-16T11:10:34Z
  • dc.date.issued 2016
  • dc.description.abstract BACKGROUND: Concurrent personality disorder (PD) and substance use disorder (SUD) are common in clinical practice. However, SUD is the main criterion for study exclusion in most psychotherapeutic studies of PD. As a result, data on treatment outcomes in patients with concurrent PD/SUD are scarce. METHODS: The study sample consisted of 51 patients diagnosed with severe PD and admitted for psychotherapeutic treatment as a part of routine mental health care. All patients were diagnosed with PD according to the Structured Clinical Interview for PD. Patients were further assessed (DSM-IV diagnostic criteria) to check for the presence of concurrent SUD, with 28 patients diagnosed with both disorders (PD-SUD). These 28 cases were then compared to the 23 patients without SUD (PD-nSUD) in terms of psychiatric hospitalizations and psychiatric emergency room (ER) visits before and during the 6-month therapeutic intervention and every 6 months thereafter for a total of 36 months. RESULTS: The baseline clinical characteristics correspond to a sample of PD patients (78% met DSM-IV criteria for borderline PD) with poor general functioning and a high prevalence of suicide attempts and self-harm behaviors. Altogether, the five outcome variables - the proportion and the number of psychiatric inpatient admissions, the number of days hospitalized, and the proportion and the number of psychiatric ER visits - improved significantly during the treatment period, and this improvement was maintained throughout the follow-up period. Although PD-SUD patients had more psychiatric hospitalizations and ER visits than PD-nSUD patients during follow-up, the differences between these two groups remained stable over the study period indicating that the treatment was equally effective in both groups. CONCLUSION: Specialized psychotherapy for severe PD can be effectively applied in patients with concurrent PD-SUD under usual practice conditions. These findings suggest that exclusion of patients with dual disorders from specialized treatments is unjustified.ca
  • dc.format.mimetype application/pdfca
  • dc.identifier.citation Lana F, Sánchez-Gil C, Adroher ND, Pérez V, Feixas G, Martí-Bonany J. et al. Comparison of treatment outcomes in severe personality disorder patients with or without substance use disorders: a 36-month prospective pragmatic follow-up study. Neuropsychiatr Dis Treat. 2016 Jun 21;12:1477-87. doi: 10.2147/NDT.S106270ca
  • dc.identifier.doi http://dx.doi.org/10.2147/NDT.S106270
  • dc.identifier.issn 1176-6328
  • dc.identifier.uri http://hdl.handle.net/10230/27782
  • dc.language.iso engca
  • dc.publisher Dove Medical Pressca
  • dc.relation.ispartof Neuropsychiatric Disease and Treatment. 2016 Jun 21;12:1477-87
  • dc.rights © 2016 Lana et al. This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.ca
  • dc.rights.accessRights info:eu-repo/semantics/openAccessca
  • dc.rights.uri https://creativecommons.org/licenses/by-nc/3.0/ca
  • dc.subject.other Trastorn límit de la personalitatca
  • dc.subject.other Psicoteràpiaca
  • dc.title Comparison of treatment outcomes in severe personality disorder patients with or without substance use disorders: a 36-month prospective pragmatic follow-up study.ca
  • dc.type info:eu-repo/semantics/articleca
  • dc.type.version info:eu-repo/semantics/publishedVersionca

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