Protein supplementation in a prehabilitation program in patients undergoing surgery for endometrial cancer

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• dc.contributor.author Sole-Sedeno, Josep M.
• dc.contributor.author Miralpeix, Ester
• dc.contributor.author Muns, Maria Dolors
• dc.contributor.author Rodriguez-Cosmen, Cristina
• dc.contributor.author Fabregó, Berta
• dc.contributor.author Kanjou, Nadwa
• dc.contributor.author Medina, Francesc-Xavier
• dc.contributor.author Mancebo Moreno, Gemma
• dc.date.accessioned 2023-09-19T06:09:55Z
• dc.date.available 2023-09-19T06:09:55Z
• dc.date.issued 2023
• dc.description.abstract Enhanced recovery after surgery (ERAS) and prehabilitation programs are multidisciplinary care pathways to reduce stress response and improve perioperative outcomes, which also include nutritional interventions. The aim of this study is to assess the impact of protein supplementation with 20 mg per day before surgery in a prehabilitation program in postoperative serum albumin, prealbumin, and total proteins in endometrial cancer patients undergoing laparoscopic surgery. Methods: A prospective study including patients who underwent laparoscopy for endometrial cancer was conducted. Three groups were identified according to ERAS and prehabilitation implementation (preERAS, ERAS, and Prehab). The primary outcome was levels of serum albumin, prealbumin, and total protein 24-48 h after surgery. Results: A total of 185 patients were included: 57 in the preERAS group, 60 in the ERAS group, and 68 in the Prehab group. There were no basal differences in serum albumin, prealbumin, or total protein between the three groups. After surgery, regardless of the nutritional intervention, the decrease in the values was also similar. Moreover, values in the Prehab group just before surgery were lower than the initial ones, despite the protein supplementation. Conclusions: Supplementation with 20 mg of protein per day does not impact serum protein levels in a prehabilitation program. Supplementations with higher quantities should be studied.
• dc.format.mimetype application/pdf
• dc.identifier.citation Sole-Sedeno JM, Miralpeix E, Muns MD, Rodriguez-Cosmen C, Fabrego B, Kanjou N, Medina FX, Mancebo G. Protein supplementation in a prehabilitation program in patients undergoing surgery for endometrial cancer. Int J Environ Res Public Health. 2023;20(8):5502. DOI: 10.3390/ijerph20085502
• dc.identifier.doi http://dx.doi.org/10.3390/ijerph20085502
• dc.identifier.issn 1661-7827
• dc.identifier.uri http://hdl.handle.net/10230/57910
• dc.language.iso eng
• dc.publisher MDPI
• dc.relation.ispartof Int J Environ Res Public Health. 2023;20(8):5502
• dc.rights © 2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
• dc.rights.accessRights info:eu-repo/semantics/openAccess
• dc.rights.uri http://creativecommons.org/licenses/by/4.0/
• dc.subject.keyword ERAS
• dc.subject.keyword Endometrial cancer
• dc.subject.keyword Prehabilitation
• dc.subject.keyword Protein supplementation
• dc.subject.keyword Surgery
• dc.title Protein supplementation in a prehabilitation program in patients undergoing surgery for endometrial cancer
• dc.type info:eu-repo/semantics/article
• dc.type.version info:eu-repo/semantics/publishedVersion